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DNA polymerases: structural diversity and common mechanisms

DNA polymerases: structural diversity and common mechanisms

http://www.wikidata.org/entity/Q29619403

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Direct detection and sequencing of damaged DNA bases tRNA(His) guanylyltransferase (THG1), a unique 3'-5' nucleotidyl transferase, shares unexpected structural homology with canonical 5'-3' DNA polymerases Crystal structure of human poly(A) polymerase gamma reveals a conserved catalytic core for canonical poly(A) polymerases Phi29 DNA polymerase residues Tyr59, His61 and Phe69 of the highly conserved ExoII motif are essential for interaction with the terminal protein Mutations in human DNA polymerase eta motif II alter bypass of DNA lesions Coupled protein domain motion in Taq polymerase revealed by neutron spin-echo spectroscopy.Replicative DNA polymerases The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability Alkaline phosphatase mono- and diesterase reactions: comparative transition state analysis The human DINB1 gene encodes the DNA polymerase Poltheta Functional roles of carboxylate residues comprising the DNA polymerase active site triad of Ty3 reverse transcriptase Conformation, protein recognition and repair of DNA interstrand and intrastrand cross-links of antitumor trans-[PtCl2(NH3)(thiazole)].Incorporation of non-nucleoside triphosphate analogues opposite to an abasic site by human DNA polymerases beta and lambda.The involvement of the aspartate triad of the active center in all catalytic activities of multisubunit RNA polymerase.Nucleotide modification at the gamma-phosphate leads to the improved fidelity of HIV-1 reverse transcriptase.Computational drug design strategies applied to the modelling of human immunodeficiency virus-1 reverse transcriptase inhibitors Structural insights into eukaryotic DNA replication Structure-function studies of DNA polymerase λ A rescue act: Translesion DNA synthesis past N(2) -deoxyguanosine adducts A Jump-from-Cavity Pyrophosphate Ion Release Assisted by a Key Lysine Residue in T7 RNA Polymerase Transcription Elongation A new paradigm of DNA synthesis: three-metal-ion catalysis.Molecular events during translocation and proofreading extracted from 200 static structures of DNA polymerase.Recombinant viral RdRps can initiate RNA synthesis from circular templates.A Locking Mechanism Regulates RNA Synthesis and Host Protein Interaction by the Hepatitis C Virus Polymerase Mechanism of Hepatitis C Virus RNA Polymerase Inhibition with Dihydroxypyrimidines Crystal structure of mammalian poly(A) polymerase in complex with an analog of ATP Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibition Structure of a bifunctional DNA primase-polymerase Crystal structure of the Pyrococcus horikoshii DNA primase-UTP complex: implications for the mechanism of primer synthesis Dual role of the RNA substrate in selectivity and catalysis by terminal uridylyl transferases A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment Bypass of DNA lesions generated during anticancer treatment with cisplatin by DNA polymerase eta A relaxed active site after exon ligation by the group I intron Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III α-Subunit Comparative Enzymology in the Alkaline Phosphatase Superfamily to Determine the Catalytic Role of an Active-Site Metal Ion The Family X DNA Polymerase from Deinococcus radiodurans Adopts a Non-standard Extended Conformation Structure of the Human Rev1–DNA–dNTP Ternary Complex Structure of Human DNA Polymerase κ Inserting dATP Opposite an 8-OxoG DNA Lesion Structural and Functional Elucidation of the Mechanism Promoting Error-prone Synthesis by Human DNA Polymerase Opposite the 7,8-Dihydro-8-oxo-2'-deoxyguanosine Adduct

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DNA polymerases: structural diversity and common mechanisms

http://www.wikidata.org/entity/Q29619403

description

1999 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

1999 թվականի հունիսին հրատարակված գիտական հոդված

@hy

article publié dans la revue scientifique Journal of Biological Chemistry

@fr

artículu científicu espublizáu en 1999

@ast

im Juni 1999 veröffentlichter wissenschaftlicher Artikel

@de

scientific article (publication date: 18 June 1999)

@en

wetenschappelijk artikel (gepubliceerd op 1999/06/18)

@nl

наукова стаття, опублікована в червні 1999

@uk

مقالة علمية (نشرت في 18-6-1999)

@ar

name

DNA polymerases: structural diversity and common mechanisms

@ast

DNA polymerases: structural diversity and common mechanisms

@en

type

label

DNA polymerases: structural diversity and common mechanisms

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DNA polymerases: structural diversity and common mechanisms

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prefLabel

DNA polymerases: structural diversity and common mechanisms

@ast

DNA polymerases: structural diversity and common mechanisms

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Journal of Biological Chemistry

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DNA polymerases: structural diversity and common mechanisms

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Structural basis for initiation of transcription from an RNA polymerase-promoter complex

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP

Crystal structure of rat DNA polymerase beta: evidence for a common polymerase mechanism

Crystal structure of Thermus aquaticus DNA polymerase

Crystal structure of bacteriophage T7 RNA polymerase at 3.3 A resolution

Structure of DNA polymerase I Klenow fragment bound to duplex DNA

Structure of Taq polymerase with DNA at the polymerase active site

Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69

Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism

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