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Modelling the long QT syndrome with induced pluripotent stem cells

Modelling the long QT syndrome with induced pluripotent stem cells

http://www.wikidata.org/entity/Q29620092

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Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview Early Repolarization Syndrome; Mechanistic Theories and Clinical Correlates Amniotic Fluid Stem Cells: A Novel Source for Modeling of Human Genetic Diseases Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Afford New Opportunities in Inherited Cardiovascular Disease Modeling Young at Heart: Pioneering Approaches to Model Nonischaemic Cardiomyopathy with Induced Pluripotent Stem Cells hiPSC-derived iMSCs: NextGen MSCs as an advanced therapeutically active cell resource for regenerative medicine Recent Advances in Disease Modeling and Drug Discovery for Diabetes Mellitus Using Induced Pluripotent Stem Cells Report from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell Replacement Genotype-phenotype correlation in long QT syndrome G-protein Coupled Receptor Signaling in Pluripotent Stem Cell-derived Cardiovascular Cells: Implications for Disease Modeling Induced Pluripotency and Gene Editing in Disease Modelling: Perspectives and Challenges Nanopatterned Human iPSC-Based Model of a Dystrophin-Null Cardiomyopathic Phenotype Parkinson's disease proteins: Novel mitochondrial targets for cardioprotection Induced pluripotent stem cells for cardiovascular disease: from product-focused disease modeling to process-focused disease discovery The history, hotspots, and trends of electrocardiogram Cardiovascular Disease Modeling Using Patient-Specific Induced Pluripotent Stem Cells Tissue engineering the cardiac microenvironment: Multicellular microphysiological systems for drug screening Modeling Viral Infectious Diseases and Development of Antiviral Therapies Using Human Induced Pluripotent Stem Cell-Derived Systems Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand?Long-QT syndrome: from genetics to management Modeling anesthetic developmental neurotoxicity using human stem cells Cardiac sodium channel Nav1.5 mutations and cardiac arrhythmia Induced pluripotent stem cell-derived cardiomyocytes for cardiovascular disease modeling and drug screening Induced pluripotent stem cell-derived cardiomyocytes in studies of inherited arrhythmias Modelling human disease with pluripotent stem cells iPSCs and small molecules: a reciprocal effort towards better approaches for drug discovery Induced pluripotent stem cells as a disease modeling and drug screening platform New opportunities: harnessing induced pluripotency for discovery in diabetes and metabolism The genomic stability of induced pluripotent stem cells Clinical and genetic determinants of torsade de pointes risk Using human induced pluripotent stem cells to treat retinal disease Pharmacogenomics of adverse drug reactions Clinical Potentials of Cardiomyocytes Derived from Patient-Specific Induced Pluripotent Stem Cells Functional cardiac tissue engineering Maturation status of sarcomere structure and function in human iPSC-derived cardiac myocytes Coupling Data Mining and Laboratory Experiments to Discover Drug Interactions Causing QT Prolongation Generation of Functional Cardiomyocytes from Efficiently Generated Human iPSCs and a Novel Method of Measuring Contractility Generation of highly purified human cardiomyocytes from peripheral blood mononuclear cell-derived induced pluripotent stem cells A robust strategy for negative selection of Cre-loxP recombination-based excision of transgenes in induced pluripotent stem cells Human iPS cell model of type 3 long QT syndrome recapitulates drug-based phenotype correction

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Modelling the long QT syndrome with induced pluripotent stem cells

http://www.wikidata.org/entity/Q29620092

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2011 nî lūn-bûn

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2011 թուականի Մարտին հրատարակուած գիտական յօդուած

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2011 թվականի մարտին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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Modelling the long QT syndrome with induced pluripotent stem cells

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Modelling the long QT syndrome with induced pluripotent stem cells

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Modelling the long QT syndrome with induced pluripotent stem cells

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Modelling the long QT syndrome with induced pluripotent stem cells

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Arbel G

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Boulos M

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Caspi O

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Feldman O

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Gepstein A

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Hammerman H

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Huber I

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Itzhaki I

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Maizels L

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P2860

Disease-specific induced pluripotent stem cells

Induced pluripotent stem cell lines derived from human somatic cells

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

Reprogramming of human somatic cells to pluripotency with defined factors

Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

Patient-specific induced pluripotent stem-cell models for long-QT syndrome

Progress toward the clinical application of patient-specific pluripotent stem cells

The impact of drug-induced QT interval prolongation on drug discovery and development.

Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties.

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scholarly article

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382419

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10.1038/NATURE09747

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1006108245

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