Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase
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Human phosphoinositide 3-kinase C2beta, the role of calcium and the C2 domain in enzyme activityStructural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85alpha Src homology 2 domains with phosphoinositides and inositol polyphosphatesSrc-family tyrosine kinases in activation of ERK-1 and p85/p110-phosphatidylinositol 3-kinase by G/CCKB receptorsGTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunitPhosphatidylinositol 3'-kinase is activated by association with IRS-1 during insulin stimulationThe SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytesFunctional interaction between c-Src and its mitotic target, Sam 68Activation of Src family kinases by colony stimulating factor-1, and their association with its receptorAlpha 2-chimerin, an SH2-containing GTPase-activating protein for the ras-related protein p21rac derived by alternate splicing of the human n-chimerin gene, is selectively expressed in brain regions and testesA tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1p190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linkingCharacterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150.Ptdins 3-kinase complexSpecific phosphopeptide binding regulates a conformational change in the PI 3-kinase SH2 domain associated with enzyme activationInteraction of p85 subunit of PI 3-kinase with insulin and IGF-1 receptors analysed by using the two-hybrid systemIn vivo binding properties of SH2 domains from GTPase-activating protein and phosphatidylinositol 3-kinaseA Ras-GTPase-activating protein SH3-domain-binding protein1-Phosphatidylinositol 3-kinase activity is required for insulin-stimulated glucose transport but not for RAS activation in CHO cellsp110delta, a novel phosphatidylinositol 3-kinase catalytic subunit that associates with p85 and is expressed predominantly in leukocytesA human phosphatidylinositol 3-kinase complex related to the yeast Vps34p-Vps15p protein sorting systemStructure of a specific peptide complex of the carboxy-terminal SH2 domain from the p85 alpha subunit of phosphatidylinositol 3-kinasePhosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivoThe SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signallingInteraction of the p85 subunit of PI 3-kinase and its N-terminal SH2 domain with a PDGF receptor phosphorylation site: structural features and analysis of conformational changesSH2 domains exhibit high-affinity binding to tyrosine-phosphorylated peptides yet also exhibit rapid dissociation and exchangeFBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascadeExpression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression systemCloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmanninIncreased insulin sensitivity in mice lacking p85beta subunit of phosphoinositide 3-kinaseMultiple forms of p55PIK, a regulatory subunit of phosphoinositide 3-kinase, are generated by alternative initiation of translationIdentification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast.Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutationIdentification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrewActivation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signalingHigh-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domainsEps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signalsMutational analysis of the Src SH3 domain: the same residues of the ligand binding surface are important for intra- and intermolecular interactionsThe SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptorsPhosphorylation of Nck in response to a variety of receptors, phorbol myristate acetate, and cyclic AMPAssociation of hematopoietic cell phosphatase with c-Kit after stimulation with c-Kit ligandMultiple SH2-mediated interactions in v-src-transformed cells.
P2860
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P2860
Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase
description
1991 nî lūn-bûn
@nan
1991 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Characterization of two 85 kd ...... -src complexes, and PI3-kinase
@ast
Characterization of two 85 kd ...... -src complexes, and PI3-kinase
@en
type
label
Characterization of two 85 kd ...... -src complexes, and PI3-kinase
@ast
Characterization of two 85 kd ...... -src complexes, and PI3-kinase
@en
prefLabel
Characterization of two 85 kd ...... -src complexes, and PI3-kinase
@ast
Characterization of two 85 kd ...... -src complexes, and PI3-kinase
@en
P2093
P3181
P1433
P1476
Characterization of two 85 kd ...... -src complexes, and PI3-kinase
@en
P2093
Panayotou G
Ruiz-Larrea F
Thompson A
P304
P3181
P356
10.1016/0092-8674(91)90411-Q
P407
P577
1991-04-05T00:00:00Z