Mutations of the VHL gene in sporadic renal cell carcinoma: definition of a risk factor for VHL patients to develop an RCC
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Prevalence of von Hippel-Lindau gene mutations in sporadic renal cell carcinoma: results from The Netherlands cohort studyGenetic and Chromosomal Aberrations and Their Clinical Significance in Renal NeoplasmsIntegrated molecular analysis of clear-cell renal cell carcinoma.Age related shift in the mutation spectra of germline and somatic NF2 mutations: hypothetical role of DNA repair mechanisms.Role of the ubiquitin proteasome system in renal cell carcinoma.The ubiquitin system, disease, and drug discovery.Pazopanib for the treatment of patients with advanced renal cell carcinomaA mutation at IVS1 + 5 of the von Hippel-Lindau gene resulting in intron retention in transcripts is not pathogenic in a patient with a tongue cancer?: case report.The erythropoietin/erythropoietin receptor signaling pathway promotes growth and invasion abilities in human renal carcinoma cells.VHL, the story of a tumour suppressor gene.A novel germline mutation of the VHL gene in a Greek family with Von Hippel-Lindau diseaseThree novel germ-line VHL mutations in Hungarian von Hippel-Lindau patients, including a nonsense mutation in a fifteen-year-old boy with renal cell carcinomaSignificance of TP53 mutations in human cancer: a critical analysis of mutations at CpG dinucleotides.von Hippel-Lindau disease: recent advances and therapeutic perspectives.E2-EPF UCP regulates stability and functions of missense mutant pVHL via ubiquitin mediated proteolysis.Characterization of VHL missense mutations in sporadic clear cell renal cell carcinoma: hotspots, affected binding domains, functional impact on pVHL and therapeutic relevanceTrichloroethylene exposure and somatic mutations of the VHL gene in patients with Renal Cell Carcinoma.Proteostasis modulators prolong missense VHL protein activity and halt tumor progressionImproved detection of germline mutations in Korean VHL patients by multiple ligation-dependent probe amplification analysisDiagnostic genetics at a distance: von hippel-lindau disease and a novel mutation.Update on novel agents in renal cell carcinoma.Pazopanib for the treatment of renal cancer.Crossing paths in Human Renal Cell Carcinoma (hRCC).Management of metastatic kidney cancer in the era of personalized medicine.Targeting carbonic anhydrase IX activity and expression.Targeted therapy for renal cell carcinoma: a new treatment paradigm.Inactivation of VHL by tumorigenic mutations that disrupt dynamic coupling of the pVHL.hypoxia-inducible transcription factor-1alpha complex.UMD (Universal mutation database): a generic software to build and analyze locus-specific databases.An integrated computational approach can classify VHL missense mutations according to risk of clear cell renal carcinoma.The bevacizumab experience in advanced renal cell carcinomaAnalysis of VHL Gene Alterations and their Relationship to Clinical Parameters in Sporadic Conventional Renal Cell CarcinomaSomatic von Hippel-Lindau disease gene mutation in clear-cell renal carcinomas associated with end-stage renal disease/acquired cystic disease of the kidney.Survival and causes of death in patients with von Hippel-Lindau disease.The FBN2 gene: new mutations, locus-specific database (Universal Mutation Database FBN2), and genotype-phenotype correlations.The HIF and other quandaries in VHL disease.Clinical presentation and mutation analysis of VHL disease in a large Chinese family.Growth kinetics in von Hippel-Lindau-associated renal cell carcinoma.Comparative analysis of germline and somatic microlesion mutational spectra in 17 human tumor suppressor genes.Von Hippel-Lindau disease.Single-cell genetic analysis validates cytopathological identification of circulating cancer cells in patients with clear cell renal cell carcinoma.
P2860
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P2860
Mutations of the VHL gene in sporadic renal cell carcinoma: definition of a risk factor for VHL patients to develop an RCC
description
1999 nî lūn-bûn
@nan
1999 թուականին հրատարակուած գիտական յօդուած
@hyw
1999 թվականին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Mutations of the VHL gene in s ...... VHL patients to develop an RCC
@ast
Mutations of the VHL gene in s ...... VHL patients to develop an RCC
@en
type
label
Mutations of the VHL gene in s ...... VHL patients to develop an RCC
@ast
Mutations of the VHL gene in s ...... VHL patients to develop an RCC
@en
prefLabel
Mutations of the VHL gene in s ...... VHL patients to develop an RCC
@ast
Mutations of the VHL gene in s ...... VHL patients to develop an RCC
@en
P2093
P2860
P3181
P1433
P1476
Mutations of the VHL gene in s ...... VHL patients to develop an RCC
@en
P2093
J M Maréchal
M T Orfanelli
P2860
P304
P3181
P356
10.1002/(SICI)1098-1004(1999)13:6<464::AID-HUMU6>3.0.CO;2-A
P407
P577
1999-01-01T00:00:00Z