The Tyrosine Kinase c-Src Specifically Binds to the Active Integrin αIIbβ3 to Initiate Outside-in Signaling in Platelets
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[New perspectives on the role of αIIbβ3 integrin in defective megakaryopoiesis].Directly Activating the Integrin αIIbβ3 Initiates Outside-In Signaling by Causing αIIbβ3 Clustering.Integrin αIIbβ3 outside-in signaling.Src family kinase tyrosine phosphorylates Toll-like receptor 4 to dissociate MyD88 and Mal/Tirap, suppressing LPS-induced inflammatory responses.2,5-Hexanedione induces dopaminergic neurodegeneration through integrin αMβ2/NADPH oxidase axis-mediated microglial activation.Roles of integrin β3 cytoplasmic tail in bidirectional signal transduction in a trans-dominant inhibition model.
P2860
The Tyrosine Kinase c-Src Specifically Binds to the Active Integrin αIIbβ3 to Initiate Outside-in Signaling in Platelets
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2015 nî lūn-bûn
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2015 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մայիսին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
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2015年论文
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name
The Tyrosine Kinase c-Src Spec ...... side-in Signaling in Platelets
@ast
The Tyrosine Kinase c-Src Spec ...... side-in Signaling in Platelets
@en
type
label
The Tyrosine Kinase c-Src Spec ...... side-in Signaling in Platelets
@ast
The Tyrosine Kinase c-Src Spec ...... side-in Signaling in Platelets
@en
prefLabel
The Tyrosine Kinase c-Src Spec ...... side-in Signaling in Platelets
@ast
The Tyrosine Kinase c-Src Spec ...... side-in Signaling in Platelets
@en
P2093
P2860
P356
P1476
The Tyrosine Kinase c-Src Spec ...... side-in Signaling in Platelets
@en
P2093
David T Moore
Hong Cheng
Joel S Bennett
Lisa M Span
William F DeGrado
P2860
P304
15825-15834
P356
10.1074/JBC.M115.648428
P407
P577
2015-05-06T00:00:00Z