Tetraspanin family member CD9 inhibits Aggrus/podoplanin-induced platelet aggregation and suppresses pulmonary metastasis.
about
Podoplanin - a small glycoprotein with many facesPodoplanin: emerging functions in development, the immune system, and cancerThe CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture.Podoplanin associates with CD44 to promote directional cell migrationCD 9 and vimentin distinguish clear cell from chromophobe renal cell carcinoma.Platelets promote tumor growth and metastasis via direct interaction between Aggrus/podoplanin and CLEC-2.SRC induces podoplanin expression to promote cell migrationTetraspanin CO-029 inhibits colorectal cancer cell movement by deregulating cell-matrix and cell-cell adhesionsExpression of Aggrus/podoplanin in bladder cancer and its role in pulmonary metastasis.Tetraspanin CD9 promotes the invasive phenotype of human fibrosarcoma cells via upregulation of matrix metalloproteinase-9.Lateral organization of membrane proteins: tetraspanins spin their web.Plant lectin can target receptors containing sialic acid, exemplified by podoplanin, to inhibit transformed cell growth and migration.SRC points the way to biomarkers and chemotherapeutic targets.Serines in the intracellular tail of podoplanin (PDPN) regulate cell motility.Platelet aggregation in the formation of tumor metastasis.Podoplanin is a component of extracellular vesicles that reprograms cell-derived exosomal proteins and modulates lymphatic vessel formationExpression and clinicopathological significance of CD9 in gastrointestinal stromal tumor.Tetraspanin protein contributions to cancer.The impact of Aggrus/podoplanin on platelet aggregation and tumour metastasis.Podoplanin: a novel regulator of tumor invasion and metastasis.Co-expression of podoplanin and fibroblast growth factor 1 predicts poor prognosis in patients with lung squamous cell carcinoma.Antibody and lectin target podoplanin to inhibit oral squamous carcinoma cell migration and viability by distinct mechanisms.Platelet "first responders" in wound response, cancer, and metastasis.Functional and biochemical studies of CD9 in fibrosarcoma cell line.Podoplanin in cancer cells is experimentally able to attenuate prolymphangiogenic and lymphogenous metastatic potentials of lung squamoid cancer cells.Knockout of the tetraspanin Cd9 in the TRAMP model of de novo prostate cancer increases spontaneous metastases in an organ-specific manner.Prevention of hematogenous metastasis by neutralizing mice and its chimeric anti-Aggrus/podoplanin antibodies.
P2860
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P2860
Tetraspanin family member CD9 inhibits Aggrus/podoplanin-induced platelet aggregation and suppresses pulmonary metastasis.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Tetraspanin family member CD9 ...... ppresses pulmonary metastasis.
@ast
Tetraspanin family member CD9 ...... ppresses pulmonary metastasis.
@en
type
label
Tetraspanin family member CD9 ...... ppresses pulmonary metastasis.
@ast
Tetraspanin family member CD9 ...... ppresses pulmonary metastasis.
@en
prefLabel
Tetraspanin family member CD9 ...... ppresses pulmonary metastasis.
@ast
Tetraspanin family member CD9 ...... ppresses pulmonary metastasis.
@en
P2093
P921
P1433
P1476
Tetraspanin family member CD9 ...... uppresses pulmonary metastasis
@en
P2093
Hiroyuki Arai
Kazuhiko Mishima
Mikihiko Naito
Naoya Fujita
Shigeo Sato
Takashi Tsuruo
Youya Nakazawa
P304
P356
10.1182/BLOOD-2007-11-124693
P407
P577
2008-06-09T00:00:00Z