Geographic patterns of Plasmodium falciparum drug resistance distinguished by differential responses to amodiaquine and chloroquine - Wikidata - wikimedia - TriplyDB

Geographic patterns of Plasmodium falciparum drug resistance distinguished by differential responses to amodiaquine and chloroquine

Geographic patterns of Plasmodium falciparum drug resistance distinguished by differential responses to amodiaquine and chloroquine

http://www.wikidata.org/entity/Q30047377

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Challenges of drug-resistant malaria Antimalarial drug resistance: An overview Antimalarial efficacy of piperaquine-based antimalarial combination therapies: facts and uncertainties Structural polymorphism in the promoter ofpfmrp2confersPlasmodium falciparumtolerance to quinoline drugs A HECT ubiquitin-protein ligase as a novel candidate gene for altered quinine and quinidine responses in Plasmodium falciparum PfCRT and its role in antimalarial drug resistance A genome wide association study of Plasmodium falciparum susceptibility to 22 antimalarial drugs in Kenya Plasmodium falciparum drug resistance in Angola Molecular evidence of increased resistance to anti-folate drugs in Plasmodium falciparum in North-East India: a signal for potential failure of artemisinin plus sulphadoxine-pyrimethamine combination therapy Temporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal Kenya Identification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparum Chloroquine clinical failures in P. falciparum malaria are associated with mutant Pfmdr-1, not Pfcrt in Madagascar PfMDR1: mechanisms of transport modulation by functional polymorphisms Pyronaridine-artesunate versus chloroquine in patients with acute Plasmodium vivax malaria: a randomized, double-blind, non-inferiority trial A process similar to autophagy is associated with cytocidal chloroquine resistance in Plasmodium falciparum Molecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite's Chloroquine Resistance Transporter Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-Aminoquinoline Drug Resistance Is Accompanied by Altered Parasite Metabolism and Digestive Vacuole Physiology Alternatively spliced transcripts and novel pseudogenes of the Plasmodium falciparum resistance-associated locus pfcrt detected in East African malaria patients Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites The effect of dosing strategies on the therapeutic efficacy of artesunate-amodiaquine for uncomplicated malaria: a meta-analysis of individual patient data A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug Piperaquine Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite's chloroquine resistance transporter Analysis of malaria parasite phenotypes using experimental genetic crosses of Plasmodium falciparum.Use of proscribed chloroquine is associated with an increased risk of pfcrt T76 mutation in some parts of Ghana.Progressive increase in point mutations associates chloroquine resistance: Even after withdrawal of chloroquine use in India Protein-based signatures of functional evolution in Plasmodium falciparum.Profile of Thomas E. Wellems Rapid evolution of fluoroquinolone-resistant Escherichia coli in Nigeria is temporally associated with fluoroquinolone use DNA repair mechanisms and their biological roles in the malaria parasite Plasmodium falciparum.Double mutation in the pfmdr1 gene is associated with emergence of chloroquine-resistant Plasmodium falciparum malaria in Eastern India Protecting the malaria drug arsenal: halting the rise and spread of amodiaquine resistance by monitoring the PfCRT SVMNT type Efficacy of artemisinin-based combination treatments of uncomplicated falciparum malaria in under-five-year-old Nigerian children.Return of chloroquine-sensitive Plasmodium falciparum parasites and emergence of chloroquine-resistant Plasmodium vivax in Ethiopia.Molecular assessment of Plasmodium falciparum resistance to antimalarial drugs in Papua New Guinea using an extended ligase detection reaction fluorescent microsphere assay.Malaria biology and disease pathogenesis: insights for new treatments.Role of Pfmdr1 in in vitro Plasmodium falciparum susceptibility to chloroquine, quinine, monodesethylamodiaquine, mefloquine, lumefantrine, and dihydroartemisinin Evidence that mutant PfCRT facilitates the transmission to mosquitoes of chloroquine-treated Plasmodium gametocytes Differential drug efflux or accumulation does not explain variation in the chloroquine response of Plasmodium falciparum strains expressing the same isoform of mutant PfCRT.Plasmodium falciparum resistance to cytocidal versus cytostatic effects of chloroquine.Assessment of molecular markers for anti-malarial drug resistance after the introduction and scale-up of malaria control interventions in western Kenya.

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P2860

Geographic patterns of Plasmodium falciparum drug resistance distinguished by differential responses to amodiaquine and chloroquine

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Proceedings of the National Academy of Sciences of the United States of America

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Geographic patterns of Plasmod ...... to amodiaquine and chloroquine

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Juliana Martha Sá

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Karen Hayton

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Pascal Ringwald

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Thomas E Wellems

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P2860

The impact of malaria parasitism: from corpuscles to communities

Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum

Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance

R/qtl: QTL mapping in experimental crosses

Short report: polymorphisms in the chloroquine resistance transporter gene in Plasmodium falciparum isolates from Lombok, Indonesia.

Short report: Molecular evaluation of the efficacy of chloroquine treatment of uncomplicated Plasmodium falciparum malaria in East Timor.

Origin and dissemination of chloroquine-resistant Plasmodium falciparum with mutant pfcrt alleles in the Philippines

Evolution of a unique Plasmodium falciparum chloroquine-resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South America

Chloroquine-resistant malaria.

Dictyostelium discoideum expresses a malaria chloroquine resistance mechanism upon transfection with mutant, but not wild-type, Plasmodium falciparum transporter PfCRT.

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