Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1.
about
Regulation of Ack1 localization and activity by the amino-terminal SAM domainAck1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancerACK1 tyrosine kinase: targeted inhibition to block cancer cell proliferationThe Cdc42-associated kinase ACK1 is not autoinhibited but requires Src for activation.A dock and coalesce mechanism driven by hydrophobic interactions governs Cdc42 binding with its effector protein ACKRegulation of ack-family nonreceptor tyrosine kinases.ACK1/TNK2 tyrosine kinase: molecular signaling and evolving role in cancers.Auto-thiophosphorylation activity of Src tyrosine kinaseIdentification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic AnalysisGlobal phosphotyrosine survey in triple-negative breast cancer reveals activation of multiple tyrosine kinase signaling pathways.Ack promotes tissue growth via phosphorylation and suppression of the Hippo pathway component Expanded.Non-receptor protein tyrosine kinases signaling pathways in normal and cancer cells.FRK suppresses the proliferation of human glioma cells by inhibiting cyclin D1 nuclear accumulation.Activated Cdc42-associated kinase 1 (Ack1) is required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor recruitment to lipid rafts and induction of cell deathA role for the non-receptor tyrosine kinase ACK1 in TNF-alpha-mediated apoptosis and proliferation in human intestinal epithelial caco-2 cells.
P2860
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P2860
Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1.
@ast
Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1.
@en
type
label
Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1.
@ast
Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1.
@en
prefLabel
Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1.
@ast
Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1.
@en
P2093
P2860
P356
P1476
Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1
@en
P2093
Azad Gucwa
Barbara P Craddock
Deborah A Brown
W Todd Miller
P2860
P304
10605-10615
P356
10.1074/JBC.M109.060459
P407
P577
2010-01-28T00:00:00Z