The Nck family of adapter proteins: regulators of actin cytoskeleton.
about
Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7.Nck in a complex containing the catalytic subunit of protein phosphatase 1 regulates eukaryotic initiation factor 2alpha signaling and cell survival to endoplasmic reticulum stressStructural insight into the binding diversity between the Tyr-phosphorylated human ephrinBs and Nck2 SH2 domainPinpointing phosphotyrosine-dependent interactions downstream of the collagen receptor DDR1Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translationThe Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeletonPhosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGFUbiquitylation-dependent downregulation of Nck regulates its functional activityNck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytesThe B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85Cooperative interactions at the SLP-76 complex are critical for actin polymerizationQuantitative phosphotyrosine proteomics of EphB2 signaling by stable isotope labeling with amino acids in cell culture (SILAC)The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin networkFunctions and regulation of circular dorsal rufflesActin remodeling by Nck regulates endothelial lumen formationWASp family verprolin-homologous protein-2 (WAVE2) and Wiskott-Aldrich syndrome protein (WASp) engage in distinct downstream signaling interactions at the T cell antigen receptor siteThe Caenorhabditis elegans Eph receptor activates NCK and N-WASP, and inhibits Ena/VASP to regulate growth cone dynamics during axon guidanceRegulation of SPIN90 phosphorylation and interaction with Nck by ERK and cell adhesionMolecular dissection of PINCH-1 reveals a mechanism of coupling and uncoupling of cell shape modulation and survivalThe adaptor molecule Nck localizes the WAVE complex to promote actin polymerization during CEACAM3-mediated phagocytosis of bacteriaProtein interactions of the vesicular glutamate transporter VGLUT1Dissecting activation of the PAK1 kinase at protrusions in living cells.Regulation of process retraction and cell migration by EphA3 is mediated by the adaptor protein Nck1Conserved interdomain linker promotes phase separation of the multivalent adaptor protein Nck.T cell specific adaptor protein (TSAd) promotes interaction of Nck with Lck and SLP-76 in T cells.SDF1α-induced interaction of the adapter proteins Nck and HS1 facilitates actin polymerization and migration in T cells.Non-overlapping functions of Nck1 and Nck2 adaptor proteins in T cell activation.Proteasomal degradation of Nck1 but not Nck2 regulates RhoA activation and actin dynamicsNck recruitment to the TCR required for ZAP70 activation during thymic development.Complex formation of EphB1/Nck/Caskin1 leads to tyrosine phosphorylation and structural changes of the Caskin1 SH3 domainIsolation of monobodies that bind specifically to the SH3 domain of the Fyn tyrosine protein kinase.Studies of novel interactions between Nck and VAV SH3 domains.The cytoplasmic adaptor protein Caskin mediates Lar signal transduction during Drosophila motor axon guidance.Adaptor protein is essential for insect cytokine signaling in hemocytes.Nck adaptors are positive regulators of the size and sensitivity of the T-cell repertoire.Autoinhibitory interaction in the multidomain adaptor protein Nck: possible roles in improving specificity and functional diversity.The adapter protein Nck: role of individual SH3 and SH2 binding modules for protein interactions in T lymphocytesNck proteins maintain the adult glomerular filtration barrier.Nck adapter proteins: functional versatility in T cellsNck adapters are involved in the formation of dorsal ruffles, cell migration, and Rho signaling downstream of the platelet-derived growth factor beta receptor.
P2860
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P2860
The Nck family of adapter proteins: regulators of actin cytoskeleton.
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The Nck family of adapter proteins: regulators of actin cytoskeleton.
@ast
The Nck family of adapter proteins: regulators of actin cytoskeleton.
@en
type
label
The Nck family of adapter proteins: regulators of actin cytoskeleton.
@ast
The Nck family of adapter proteins: regulators of actin cytoskeleton.
@en
prefLabel
The Nck family of adapter proteins: regulators of actin cytoskeleton.
@ast
The Nck family of adapter proteins: regulators of actin cytoskeleton.
@en
P2093
P1433
P1476
The Nck family of adapter proteins: regulators of actin cytoskeleton.
@en
P2093
Livius Wunderlich
László Buday
Peter Tamás
P304
P356
10.1016/S0898-6568(02)00027-X
P577
2002-09-01T00:00:00Z