SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading. - Wikidata - wikimedia - TriplyDB

SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading.

SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading.

http://www.wikidata.org/entity/Q30167497

about

Differential regulation of cell motility and invasion by FAK Alternative splicing controls the mechanisms of FAK autophosphorylation Visualization of Src and FAK activity during the differentiation process from HMSCs to osteoblasts Cardiomyocyte apoptosis triggered by RAFTK/pyk2 via Src kinase is antagonized by paxillin SH3 domain of c-Src governs its dynamics at focal adhesions and the cell membrane.c-Src associates with ErbB2 through an interaction between catalytic domains and confers enhanced transforming potential.Src kinase activity and SH2 domain regulate the dynamics of Src association with lipid and protein targets.Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness.Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3.Decipher the dynamic coordination between enzymatic activity and structural modulation at focal adhesions in living cells BCAR3 regulates Src/p130 Cas association, Src kinase activity, and breast cancer adhesion signaling Phosphorylation of p130Cas initiates Rac activation and membrane ruffling.FERM domain interaction promotes FAK signaling.Initiation of attachment and generation of mature focal adhesions by integrin-containing filopodia in cell spreading.Regulation of focal adhesion turnover by ErbB signalling in invasive breast cancer cells.A small fibronectin-mimicking protein from bacteria induces cell spreading and focal adhesion formation.A biosensor generated via high-throughput screening quantifies cell edge Src dynamics Regulation of local expression of cell adhesion and motility-related mRNAs in breast cancer cells by IMP1/ZBP1 Detection of focal adhesion kinase activation at membrane microdomains by fluorescence resonance energy transfer Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation In situ photoactivation of a caged phosphotyrosine peptide derived from focal adhesion kinase temporarily halts lamellar extension of single migrating tumor cells.CrkII regulates focal adhesion kinase activation by making a complex with Crk-associated substrate, p130Cas.Src-dependent ezrin phosphorylation in adhesion-mediated signaling Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras.Polyamine-dependent activation of Rac1 is stimulated by focal adhesion-mediated Tiam1 activation Transmembrane phosphoprotein Cbp senses cell adhesion signaling mediated by Src family kinase in lipid rafts.Src SH2 arginine 175 is required for cell motility: specific focal adhesion kinase targeting and focal adhesion assembly function The effect of differentiation induction on FAK and Src activity in live HMSCs visualized by FRET.c-Src inactivation reduces renal epithelial cell-matrix adhesion, proliferation, and cyst formation Integrin αIIbβ3 transmembrane domain separation mediates bi-directional signaling across the plasma membrane.A glycosphingolipid/caveolin-1 signaling complex inhibits motility of human ovarian carcinoma cells.Activity and distribution of paxillin, focal adhesion kinase, and cadherin indicate cooperative roles during zebrafish morphogenesis Fibronectin induces endothelial cell migration through β1 integrin and Src-dependent phosphorylation of fibroblast growth factor receptor-1 at tyrosines 653/654 and 766.SH2 Ligand-Like Effects of Second Cytosolic Domain of Na/K-ATPase α1 Subunit on Src Kinase.Hic-5 promotes invadopodia formation and invasion during TGF-β-induced epithelial-mesenchymal transition.SHP-2 activates signaling of the nuclear factor of activated T cells to promote skeletal muscle growth.PTP alpha regulates integrin-stimulated FAK autophosphorylation and cytoskeletal rearrangement in cell spreading and migration Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration Src promotes cutaneous wound healing by regulating MMP-2 through the ERK pathway.Phorbol 12-myristate 13-acetate-dependent protein kinase C delta-Tyr311 phosphorylation in cardiomyocyte caveolae.

P2860

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P2860

SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading.

http://www.wikidata.org/entity/Q30167497

description

2002 nî lūn-bûn

@nan

2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

SRC catalytic but not scaffold ...... migration, and cell spreading.

@ast

SRC catalytic but not scaffold ...... migration, and cell spreading.

@en

type

label

SRC catalytic but not scaffold ...... migration, and cell spreading.

@ast

SRC catalytic but not scaffold ...... migration, and cell spreading.

@en

prefLabel

SRC catalytic but not scaffold ...... migration, and cell spreading.

@ast

SRC catalytic but not scaffold ...... migration, and cell spreading.

@en

P1433

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P932

Q30167497-48CC0CE1-E87C-4C97-BEA2-CF403D371E6B

P356

MCB.22.8.2427-2440.2002

P1433

Molecular and Cellular Biology

P1476

SRC catalytic but not scaffold ...... migration, and cell spreading.

@en

P2093

Christoph Sachsenmaier

http://www.w3.org/2001/XMLSchema#string

Jonathan A Cooper

http://www.w3.org/2001/XMLSchema#string

Leslie A Cary

http://www.w3.org/2001/XMLSchema#string

Richard A Klinghoffer

http://www.w3.org/2001/XMLSchema#string

P2860

ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

Integrin signalling: a new Cas(t) of characters enters the stage

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration.

Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substrates

Mutational analysis of the Src SH3 domain: the same residues of the ligand binding surface are important for intra- and intermolecular interactions

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

P304

2427-2440

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P31

scholarly article

P356

10.1128/MCB.22.8.2427-2440.2002

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P407

P433

8

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P478

22

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P577

2002-04-01T00:00:00Z

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P698

11909938

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P921

phosphorylation

P932

133722

http://www.w3.org/2001/XMLSchema#string