Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases.
about
Downregulation of the tumor-suppressor miR-16 via progestin-mediated oncogenic signaling contributes to breast cancer developmentIdentification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1Progesterone receptor induces ErbB-2 nuclear translocation to promote breast cancer growth via a novel transcriptional effect: ErbB-2 function as a coactivator of Stat3Regulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibitionNon-cysteine linked MUC1 cytoplasmic dimers are required for Src recruitment and ICAM-1 binding induced cell invasionJun dimerization protein 2 functions as a progesterone receptor N-terminal domain coactivator.The further redefining of steroid-mediated signalingMultimodal regulation of E2F1 gene expression by progestinsA novel computational biostatistics approach implies impaired dephosphorylation of growth factor receptors as associated with severity of autism.Membrane progesterone receptors: evidence for neuroprotective, neurosteroid signaling and neuroendocrine functions in neuronal cellsProtein tyrosine kinase signaling during oocyte maturation and fertilizationProgesterone receptor A (PRA) and PRB-independent effects of progesterone on gonadotropin-releasing hormone releaseAndrogen actions on endothelium functions and cardiovascular diseasesRapid steroid hormone actions initiated at the cell surface and the receptors that mediate them with an emphasis on recent progress in fish modelsSRC-family tyrosine kinases in oogenesis, oocyte maturation and fertilization: an evolutionary perspectiveMolecular determinants of context-dependent progesterone receptor action in breast cancerThe importance of non-nuclear AR signaling in prostate cancer progression and therapeutic resistanceThe rapid effects of 1,25-dihydroxyvitamin D3 require the vitamin D receptor and influence 24-hydroxylase activity: studies in human skin fibroblasts bearing vitamin D receptor mutationsDok-R binds c-Abl and regulates Abl kinase activity and mediates cytoskeletal reorganizationMNAR functionally interacts with both NH2- and COOH-terminal GR domains to modulate transactivationProgesterone receptor-B enhances estrogen responsiveness of breast cancer cells via scaffolding PELP1- and estrogen receptor-containing transcription complexesSmoothelin-like 1 protein is a bifunctional regulator of the progesterone receptor during pregnancyAssessment of Anti-TNF-α Activities in Keratinocytes Expressing Inducible TNF- α: A Novel Tool for Anti-TNF-α Drug ScreeningDependence of peroxisome proliferator-activated receptor ligand-induced mitogen-activated protein kinase signaling on epidermal growth factor receptor transactivationTwo domains of the progesterone receptor interact with the estrogen receptor and are required for progesterone activation of the c-Src/Erk pathway in mammalian cellsDrug development against metastasis-related genes and their pathways: A rationale for cancer therapyProgesterone receptor (PR) polyproline domain (PPD) mediates inhibition of epidermal growth factor receptor (EGFR) signaling in non-small cell lung cancer cells.Identification of a Novel Coregulator, SH3YL1, That Interacts With the Androgen Receptor N-Terminus.Phospholipase C and D regulation of Src, calcium release and membrane fusion during Xenopus laevis development.Interaction between the SH3 domain of Src family kinases and the proline-rich motif of HTLV-1 p13: a novel mechanism underlying delivery of Src family kinases to mitochondria.C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family tyrosine kinases.Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain.Membrane initiated estrogen signaling in breast cancer.Linkage of progestin and epidermal growth factor signaling: phosphorylation of progesterone receptors mediates transcriptional hypersensitivity and increased ligand-independent breast cancer cell growth.Microarray-based analysis of fish egg quality after natural or controlled ovulationProgesterone receptor rapid signaling mediates serine 345 phosphorylation and tethering to specificity protein 1 transcription factors.Lactation failure in Src knockout mice is due to impaired secretory activation.Extra-nuclear signaling of progesterone receptor to breast cancer cell movement and invasion through the actin cytoskeleton.Progesterone receptors act as sensors for mitogenic protein kinases in breast cancer models.Signaling inputs to progesterone receptor gene regulation and promoter selectivity.
P2860
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P2860
Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases.
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Progesterone receptor contains ...... c-Src family tyrosine kinases.
@ast
Progesterone receptor contains ...... c-Src family tyrosine kinases.
@en
type
label
Progesterone receptor contains ...... c-Src family tyrosine kinases.
@ast
Progesterone receptor contains ...... c-Src family tyrosine kinases.
@en
prefLabel
Progesterone receptor contains ...... c-Src family tyrosine kinases.
@ast
Progesterone receptor contains ...... c-Src family tyrosine kinases.
@en
P2093
P1433
P1476
Progesterone receptor contains ...... c-Src family tyrosine kinases.
@en
P2093
Anderson SM
Boonyaratanakornkit V
Edwards DP
P304
P356
10.1016/S1097-2765(01)00304-5
P577
2001-08-01T00:00:00Z