Experiment and theory highlight role of native state topology in SH3 folding.
about
The extracellular human melanoma inhibitory activity (MIA) protein adopts an SH3 domain-like fold.Ultrafast folding of WW domains without structured aromatic clusters in the denatured stateProtein folding: then and nowPFD: a database for the investigation of protein folding kinetics and stabilityUsing flexible loop mimetics to extend -value analysis to secondary structure interactionsTheoretical and experimental demonstration of the importance of specific nonnative interactions in protein foldingProtein sectors: evolutionary units of three-dimensional structureMolecular mechanism of a temperature-sensitive phenotype in peroxisomal biogenesis disorderOn the precision of experimentally determined protein folding rates and phi-valuesConstructing sequence-dependent protein models using coevolutionary information.Electrostatic effects in the folding of the SH3 domain of the c-Src tyrosine kinase: pH-dependence in 3D-domain swapping and amyloid formationPropensity to form amyloid fibrils is encoded as excitations in the free energy landscape of monomeric proteins.Insights into the folding and unfolding processes of wild-type and mutated SH3 domain by molecular dynamics and replica exchange molecular dynamics simulations.Transient helical structure during PI3K and Fyn SH3 domain folding.The dominant folding route minimizes backbone distortion in SH3.Interfacial water molecules in SH3 interactions: Getting the full picture on polyproline recognition by protein-protein interaction domains.A residue in helical conformation in the native state adopts a β-strand conformation in the folding transition state despite its high and canonical Φ-value.Kinetic consequences of native state optimization of surface-exposed electrostatic interactions in the Fyn SH3 domain.The redundancy of NMR restraints can be used to accelerate the unfolding behavior of an SH3 domain during molecular dynamics simulationsInterdomain Contacts Control Native State Switching of RfaH on a Dual-Funneled LandscapeConstraining local structure can speed up folding by promoting structural polarization of the folding pathwayTurbulent phenomena in protein folding.Relaxation dispersion NMR spectroscopy as a tool for detailed studies of protein folding.The osmolyte trimethylamine-N-oxide stabilizes the Fyn SH3 domain without altering the structure of its folding transition state.Folding energy landscape and network dynamics of small globular proteinsEarly events in protein folding: Is there something more than hydrophobic burst?Phi-value analysis of a three-state protein folding pathway by NMR relaxation dispersion spectroscopy.Similarity and difference in the unfolding of thermophilic and mesophilic cold shock proteins studied by molecular dynamics simulationsSequence of events in folding mechanism: beyond the Gō modelP versus Q: structural reaction coordinates capture protein folding on smooth landscapes.Sparsely populated folding intermediates of the Fyn SH3 domain: matching native-centric essential dynamics and experimentMultiple folding pathways of the SH3 domain.Transition states for protein folding have native topologies despite high structural variability.Formation of the folding nucleus of an SH3 domain investigated by loosely coupled molecular dynamics simulations.A binding event converted into a folding event.Calculation of mutational free energy changes in transition states for protein folding.Posttransition state desolvation of the hydrophobic core of the src-SH3 protein domainStructural and kinetic characterization of the simplified SH3 domain FP1.Folding of a highly conserved diverging turn motif from the SH3 domain.Backbone dynamics of the human MIA protein studied by (15)N NMR relaxation: implications for extended interactions of SH3 domains.
P2860
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P2860
Experiment and theory highlight role of native state topology in SH3 folding.
description
1999 nî lūn-bûn
@nan
1999 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Experiment and theory highlight role of native state topology in SH3 folding.
@ast
Experiment and theory highlight role of native state topology in SH3 folding.
@en
type
label
Experiment and theory highlight role of native state topology in SH3 folding.
@ast
Experiment and theory highlight role of native state topology in SH3 folding.
@en
prefLabel
Experiment and theory highlight role of native state topology in SH3 folding.
@ast
Experiment and theory highlight role of native state topology in SH3 folding.
@en
P2093
P356
P1476
Experiment and theory highlight role of native state topology in SH3 folding.
@en
P2093
P304
P356
10.1038/14901
P577
1999-11-01T00:00:00Z