ATM associates with and phosphorylates p53: mapping the region of interaction. - Wikidata - wikimedia - TriplyDB

ATM associates with and phosphorylates p53: mapping the region of interaction.

ATM associates with and phosphorylates p53: mapping the region of interaction.

http://www.wikidata.org/entity/Q30175960

about

Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks Glioma oncoprotein Bcl2L12 inhibits the p53 tumor suppressor Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: a potential link between genome surveillance and apoptosis Targeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53 ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage Involvement of human MOF in ATM function Transcriptional regulation of the mdm2 oncogene by p53 requires TRRAP acetyltransferase complexes A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival.ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1 Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damage Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53 Immunoglobulin class switch recombination is impaired in Atm-deficient mice Glycerol restores heat-induced p53-dependent apoptosis of human glioblastoma cells bearing mutant p53 The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response Differential role of RB in response to UV and IR damage.p53 Acetylation: Regulation and Consequences Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity Functional link between BLM defective in Bloom's syndrome and the ataxia-telangiectasia-mutated protein, ATM Regulatory interactions between the checkpoint kinase Chk1 and the proteins of the DNA-dependent protein kinase complex Plk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathway BRCA1-BARD1 complexes are required for p53Ser-15 phosphorylation and a G1/S arrest following ionizing radiation-induced DNA damage Cisplatinum and taxol induce different patterns of p53 phosphorylation ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm c-Abl is required for development and optimal cell proliferation in the context of p53 deficiency The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins Efficient Activation of Apoptotic Signaling during Mitotic Arrest with AK301 Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage The role of the DNA damage response kinase ataxia telangiectasia mutated in neuroprotection DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM Ionizing radiation activates nuclear protein phosphatase-1 by ATM-dependent dephosphorylation.Depletion of the adaptor protein NCK increases UV-induced p53 phosphorylation and promotes apoptosis.The yin-yang of DNA damage response: roles in tumorigenesis and cellular senescence.Variants in the ATM gene associated with a reduced risk of contralateral breast cancer.Autophosphorylation and ATM activation: additional sites add to the complexity.

P2860

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P2860

ATM associates with and phosphorylates p53: mapping the region of interaction.

http://www.wikidata.org/entity/Q30175960

description

1998 nî lūn-bûn

@nan

1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

1998年の論文

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1998年論文

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1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

ATM associates with and phosphorylates p53: mapping the region of interaction.

@ast

ATM associates with and phosphorylates p53: mapping the region of interaction.

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type

label

ATM associates with and phosphorylates p53: mapping the region of interaction.

@ast

ATM associates with and phosphorylates p53: mapping the region of interaction.

@en

prefLabel

ATM associates with and phosphorylates p53: mapping the region of interaction.

@ast

ATM associates with and phosphorylates p53: mapping the region of interaction.

@en

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Nature Genetics

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ATM associates with and phosphorylates p53: mapping the region of interaction.

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P2093

Chan D

http://www.w3.org/2001/XMLSchema#string

Gabrielli B

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Gatei M

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Hobson K

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Keating KE

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Khanna KK

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Kozlov S

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Lavin MF

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Lees-Miller SP

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Scott S

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398-400

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scholarly article

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10.1038/3882

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P433

4

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P478

20

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1998-12-01T00:00:00Z

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232794603

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9843217

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phosphorylation