The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1.
about
PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodiaDimerization via tandem leucine zippers is essential for the activation of the mitogen-activated protein kinase kinase kinase, MLK-3PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organizationTransactivation of naturally occurring HIV-1 long terminal repeats by the JNK signaling pathway. The most frequent naturally occurring length polymorphism sequence introduces a novel binding site for AP-1 factorsCdc42-induced activation of the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and changes in phosphorylationMAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinaseThe kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylationIdentification and characterization of functional domains in a mixed lineage kinase LZKMRK, a mixed lineage kinase-related molecule that plays a role in gamma-radiation-induced cell cycle arrestA new identity for MLK3 as an NIMA-related, cell cycle-regulated kinase that is localized near centrosomes and influences microtubule organization.Scaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathwayRegulation of mixed lineage kinase 3 is required for Neurofibromatosis-2-mediated growth suppression in human cancerA human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathwaysSH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1Mixed lineage kinase LZK and antioxidant protein-1 activate NF-kappaB synergisticallyMixed-lineage kinase 2-SH3 domain binds dynamin and greatly enhances activation of GTPase by phospholipidHuman mitogen-activated protein kinase kinase kinase mediates the stress-induced activation of mitogen-activated protein kinase cascadesMEK kinases are regulated by EGF and selectively interact with Rac/Cdc42The MAP kinase kinase kinase MLK2 co-localizes with activated JNK along microtubules and associates with kinesin superfamily motor KIF3A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathwaysRegulation of IL-4 expression by the transcription factor JunB during T helper cell differentiationInteraction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascadeThe MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosisMixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complexActivation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1MLK3 Signaling in Cancer InvasionDifferential activation of stress-activated protein kinase kinases SKK4/MKK7 and SKK1/MKK4 by the mixed-lineage kinase-2 and mitogen-activated protein kinase kinase (MKK) kinase-1Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-betaThe mixed lineage kinase DLK utilizes MKK7 and not MKK4 as substrateLocalization of the mixed-lineage kinase DLK/MUK/ZPK to the Golgi apparatus in NIH 3T3 cellsRas participates in the activation of p38 MAPK by interleukin-1 by associating with IRAK, IRAK2, TRAF6, and TAK-1Negative regulation of mixed lineage kinase 3 by protein kinase B/AKT leads to cell survivalMST/MLK2, a member of the mixed lineage kinase family, directly phosphorylates and activates SEK1, an activator of c-Jun N-terminal kinase/stress-activated protein kinaseDifferential activation of two JNK activators, MKK7 and SEK1, by MKN28-derived nonreceptor serine/threonine kinase/mixed lineage kinase 2The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinasesCloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathwayIsolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascadesMixed lineage kinase 3 (MLK3)-activated p38 MAP kinase mediates transforming growth factor-beta-induced apoptosis in hepatoma cellsIsolation of the protein kinase TAO2 and identification of its mitogen-activated protein kinase/extracellular signal-regulated kinase kinase binding domainExpression of mitogen-activated protein kinase pathways during postnatal development of rat heart
P2860
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P2860
The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1.
description
1996 nî lūn-bûn
@nan
1996 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
The mixed lineage kinase SPRK ...... otein kinase activator, SEK-1.
@ast
The mixed lineage kinase SPRK ...... otein kinase activator, SEK-1.
@en
type
label
The mixed lineage kinase SPRK ...... otein kinase activator, SEK-1.
@ast
The mixed lineage kinase SPRK ...... otein kinase activator, SEK-1.
@en
prefLabel
The mixed lineage kinase SPRK ...... otein kinase activator, SEK-1.
@ast
The mixed lineage kinase SPRK ...... otein kinase activator, SEK-1.
@en
P2093
P2860
P356
P1476
The mixed lineage kinase SPRK ...... otein kinase activator, SEK-1.
@en
P2093
Godowski P
Kyriakis JM
P2860
P304
19025-19028
P356
10.1074/JBC.271.32.19025
P407
P577
1996-08-01T00:00:00Z