Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri
about
Growth transformation of human T cells by herpesvirus saimiri requires multiple Tip-Lck interaction motifsTyrosine phosphorylation of the Tio oncoprotein is essential for transformation of primary human T cellsActivation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane proteinMulti-transmembrane protein K15 of Kaposi's sarcoma-associated herpesvirus targets Lyn kinase in the membrane raft and induces NFAT/AP1 activities.Identification of the novel K15 gene at the rightmost end of the Kaposi's sarcoma-associated herpesvirus genome.Herpesvirus ateles gene product Tio interacts with nonreceptor protein tyrosine kinasesThe Lck binding domain of herpesvirus saimiri tip-484 constitutively activates Lck and STAT3 in T cells.Mutation of the Lck-binding motif of Tip enhances lymphoid cell activation by herpesvirus saimiri.Simian homologues of human herpesvirus 8Herpesvirus saimiri.Analysis of gene expression in a human cell line stably transduced with herpesvirus saimiri.Signaling activities of gammaherpesvirus membrane proteinsDownregulation of p56(lck) tyrosine kinase activity in T cells of squirrel monkeys (Saimiri sciureus) correlates with the nontransforming and apathogenic properties of herpesvirus saimiri in its natural hostEvolutionary aspects of oncogenic herpesvirusesAssociation of herpesvirus saimiri tip with lipid raft is essential for downregulation of T-cell receptor and CD4 coreceptor.Suppression of tetradecanoyl phorbol acetate-induced lytic reactivation of Kaposi's sarcoma-associated herpesvirus by K1 signal transductionRegulation of the herpesvirus saimiri oncogene stpC, similar to that of T-cell activation genes, in growth-transformed human T lymphocytes.Functional phenotype of transformed human alphabeta and gammadelta T cells determined by different subgroup C strains of herpesvirus SaimiriSystematic mutagenesis of the murine gammaherpesvirus 68 M2 protein identifies domains important for chronic infection.Viral modulation of T-cell receptor signalingThe superantigen-homologous viral immediate-early gene ie14/vsag in herpesvirus saimiri-transformed human T cells.Use of virion DNA as a cloning vector for the construction of mutant and recombinant herpesvirusesModulating p56Lck in T-Cells by a Chimeric Peptide Comprising Two Functionally Different Motifs of Tip from Herpesvirus saimiri.Primary structure of the Herpesvirus ateles genomeSTP and Tip are essential for herpesvirus saimiri oncogenicityHerpesvirus saimiri Tip-484 membrane protein markedly increases p56lck activity in T cellsEnhanced downregulation of Lck-mediated signal transduction by a Y114 mutation of herpesvirus Saimiri tip.T-cell growth transformation by herpesvirus saimiri is independent of STAT3 activation.
P2860
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P2860
Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri
description
1995 nî lūn-bûn
@nan
1995 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
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1995年学术文章
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1995年学术文章
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1995年学术文章
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1995年学术文章
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1995年学术文章
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1995年學術文章
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name
Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri
@ast
Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri
@en
type
label
Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri
@ast
Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri
@en
prefLabel
Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri
@ast
Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri
@en
P2093
P2860
P1433
P1476
Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiri
@en
P2093
P2860
P304
P577
1995-12-01T00:00:00Z