Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway.
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RGS3 inhibits G protein-mediated signaling via translocation to the membrane and binding to Galpha11Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i)beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2Alpha(2) adrenoceptors regulate proliferation of human intestinal epithelial cellsLong-Term Potentiation and MemoryThe effects of repetitive vibration on sensorineural function: biomarkers of sensorineural injury in an animal model of metabolic syndromeInteraction between G proteins and tyrosine kinases upon T cell receptor.CD3-mediated signalingTwo human cDNAs, including a homolog of Arabidopsis FUS6 (COP11), suppress G-protein- and mitogen-activated protein kinase-mediated signal transduction in yeast and mammalian cellsMEK1 promotes YAP and their interaction is critical for tumorigenesis in liver cancerDifferential effect of the inhibition of Grb2-SH3 interactions in platelet activation induced by thrombin and by Fc receptor engagementThe heterotrimeric G q protein-coupled angiotensin II receptor activates p21 ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytesMitogenic signaling via endogenous kappa-opioid receptors in C6 glioma cells: evidence for the involvement of protein kinase C and the mitogen-activated protein kinase signaling cascadeA novel membrane glycoprotein, SHPS-1, that binds the SH2-domain-containing protein tyrosine phosphatase SHP-2 in response to mitogens and cell adhesionBiological significance of agmatine, an endogenous ligand at imidazoline binding sitesEvidence for the involvement of Gi2 in activation of extracellular signal-regulated kinases in hepatocytesRegulation of extracellular-signal regulated kinase and c-Jun N-terminal kinase by G-protein-linked muscarinic acetylcholine receptorsStimulation of Ras guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) upon tyrosine phosphorylation by the Cdc42-regulated kinase ACK1Intracellular signaling mechanisms leading to synergistic effects of endothelin-1 and stem cell factor on proliferation of cultured human melanocytes. Cross-talk via trans-activation of the tyrosine kinase c-kit receptorThe inhibitory gamma subunit of the type 6 retinal cGMP phosphodiesterase functions to link c-Src and G-protein-coupled receptor kinase 2 in a signaling unit that regulates p42/p44 mitogen-activated protein kinase by epidermal growth factorSignaling via Shc family adapter proteinsN-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signalingProgression of coronary atherosclerosis is associated with a common genetic variant of the human stromelysin-1 promoter which results in reduced gene expressionSrc-family tyrosine kinases, phosphoinositide 3-kinase and Gab1 regulate extracellular signal-regulated kinase 1 activation induced by the type A endothelin-1 G-protein-coupled receptorCloning and characterization of mPAL, a novel Shc SH2 domain-binding protein expressed in proliferating cellsG protein-coupled cholecystokinin-B/gastrin receptors are responsible for physiological cell growth of the stomach mucosa in vivoDistinct signaling functions for Shc isoforms in the heartThe proximal portion of the COOH terminus of the oxytocin receptor is required for coupling to g(q), but not g(i). Independent mechanisms for elevating intracellular calcium concentrations from intracellular storesA novel pathway from phosphorylation of tyrosine residues 239/240 of Shc, contributing to suppress apoptosis by IL-3Shc interaction with Src homology 2 domain containing inositol phosphatase (SHIP) in vivo requires the Shc-phosphotyrosine binding domain and two specific phosphotyrosines on SHIPThe N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calciumDirect binding of activated c-Src to the beta 3-adrenergic receptor is required for MAP kinase activation.Integrin engagement, the actin cytoskeleton, and c-Src are required for the calcitonin-induced tyrosine phosphorylation of paxillin and HEF1, but not for calcitonin-induced Erk1/2 phosphorylation.Gi-mediated activation of the Ras/MAP kinase pathway involves a 100 kDa tyrosine-phosphorylated Grb2 SH3 binding protein, but not Src nor ShcEvidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivoNovel form of crosstalk between G protein and tyrosine kinase pathwaysInactivation of raf-1 by a protein-tyrosine phosphatase stimulated by GTP and reconstituted by Galphai/o subunits.A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics.Up-regulation of endothelial nitric-oxide synthase promoter by the phosphatidylinositol 3-kinase gamma /Janus kinase 2/MEK-1-dependent pathway.Role of dynamin, Src, and Ras in the protein kinase C-mediated activation of ERK by gonadotropin-releasing hormone.The beta3-adrenergic receptor activates mitogen-activated protein kinase in adipocytes through a Gi-dependent mechanism.
P2860
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P2860
Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway.
description
1995 nî lūn-bûn
@nan
1995 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
name
Receptor-tyrosine-kinase- and ...... y a common signalling pathway.
@ast
Receptor-tyrosine-kinase- and ...... y a common signalling pathway.
@en
type
label
Receptor-tyrosine-kinase- and ...... y a common signalling pathway.
@ast
Receptor-tyrosine-kinase- and ...... y a common signalling pathway.
@en
prefLabel
Receptor-tyrosine-kinase- and ...... y a common signalling pathway.
@ast
Receptor-tyrosine-kinase- and ...... y a common signalling pathway.
@en
P2093
P356
P1433
P1476
Receptor-tyrosine-kinase- and ...... y a common signalling pathway.
@en
P2093
Krueger KM
Lefkowitz RJ
Luttrell DK
Luttrell LM
van Biesen T
P2888
P304
P356
10.1038/376781A0
P407
P577
1995-08-01T00:00:00Z
P6179
1045781397