Activation of Bruton's tyrosine kinase (BTK) by a point mutation in its pleckstrin homology (PH) domain.
about
Txk, a nonreceptor tyrosine kinase of the Tec family, is expressed in T helper type 1 cells and regulates interferon gamma production in human T lymphocytesABL tyrosine kinases: evolution of function, regulation, and specificityEtk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cellsPleckstrin associates with plasma membranes and induces the formation of membrane projections: requirements for phosphorylation and the NH2-terminal PH domainN terminus of Sos1 Ras exchange factor: critical roles for the Dbl and pleckstrin homology domainsStructure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemiaRegulation of nuclear localization and transcriptional activity of TFII-I by Bruton's tyrosine kinaseTruncation of C-mip (Tc-mip), a new proximal signaling protein, induces c-maf Th2 transcription factor and cytoskeleton reorganizationA novel B lymphocyte-associated adaptor protein, Bam32, regulates antigen receptor signaling downstream of phosphatidylinositol 3-kinaseRole of Akt signaling in resistance to DNA-targeted therapyInteraction of SLP adaptors with the SH2 domain of Tec family kinasesProtein-tyrosine phosphatase D1, a potential regulator and effector for Tec family kinasesPhosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cellsBiochemical interactions integrating Itk with the T cell receptor-initiated signaling cascadeThe Bmx tyrosine kinase is activated by IL-3 and G-CSF in a PI-3K dependent mannerUnifying concepts in CD28, ICOS and CTLA4 co-receptor signallingThe proline rich region of the Tec homology domain of ITK regulates its activityPhosphoinositide 3-OH kinase activates the beta2 integrin adhesion pathway and induces membrane recruitment of cytohesin-1The role of Tec protein-tyrosine kinase in T cell signalingPKCbeta modulates antigen receptor signaling via regulation of Btk membrane localizationPhosphoinositide-dependent activation of the ADP-ribosylation factor GTPase-activating protein ASAP1. Evidence for the pleckstrin homology domain functioning as an allosteric siteIdentification and characterization of a molecule, BAM11, that associates with the pleckstrin homology domain of mouse BtkRegulation of nucleocytoplasmic shuttling of Bruton's tyrosine kinase (Btk) through a novel SH3-dependent interaction with ankyrin repeat domain 54 (ANKRD54).In situ detection of activated Bruton's tyrosine kinase in the Ig signaling complex by phosphopeptide-specific monoclonal antibodies.Molecular and structural characterization of five novel mutations in the Bruton's tyrosine kinase gene from patients with X-linked agammaglobulinemiaClinical targeting of mutated and wild-type protein tyrosine kinases in cancer.Phosphatidylinositol 3-kinase-gamma activates Bruton's tyrosine kinase in concert with Src family kinases.Early B cell defects.Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation.Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase.Tec/Bmx non-receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Galpha12/13Molecular modeling of the membrane targeting of phospholipase C pleckstrin homology domains.The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species.Use of Tag single nucleotide polymorphisms (SNPs) to screen PTPN21: no association with Graves' disease.Calmodulin and PI(3,4,5)P₃ cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production.Posttranscriptional regulation of Bruton's tyrosine kinase expression in antigen receptor-stimulated splenic B cells.syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction.Bruton's tyrosine kinase regulates the activation of gene rearrangements at the lambda light chain locus in precursor B cells in the mouseInvolvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production.Independent and opposing roles for Btk and lyn in B and myeloid signaling pathways.
P2860
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P2860
Activation of Bruton's tyrosine kinase (BTK) by a point mutation in its pleckstrin homology (PH) domain.
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Activation of Bruton's tyrosin ...... eckstrin homology (PH) domain.
@ast
Activation of Bruton's tyrosin ...... eckstrin homology (PH) domain.
@en
type
label
Activation of Bruton's tyrosin ...... eckstrin homology (PH) domain.
@ast
Activation of Bruton's tyrosin ...... eckstrin homology (PH) domain.
@en
prefLabel
Activation of Bruton's tyrosin ...... eckstrin homology (PH) domain.
@ast
Activation of Bruton's tyrosin ...... eckstrin homology (PH) domain.
@en
P2093
P1433
P1476
Activation of Bruton's tyrosin ...... eckstrin homology (PH) domain.
@en
P2093
A Satterthwaite
M H Havlik
P304
P356
10.1016/1074-7613(95)90026-8
P407
P577
1995-05-01T00:00:00Z