enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties.
about
Drosophila as a genetic and cellular model for studies on axonal growthRegulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase IScar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffoldIsolation and characterization of a novel class II histone deacetylase, HDAC10Structural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP.ABL tyrosine kinases: evolution of function, regulation, and specificityNESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylationAbelson phosphorylation of CLASP2 modulates its association with microtubules and actinCDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASPA novel proline-rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family.Actin-based motility of intracellular microbial pathogensGenes regulating dendritic outgrowth, branching, and routing in DrosophilaActin dynamics in plateletsDual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinityRegulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contextsRole of proteins of the Ena/VASP family in actin-based motility of Listeria monocytogenesTIPsy tour guides: how microtubule plus-end tracking proteins (+TIPs) facilitate axon guidanceThe Drosophila actin regulator ENABLED regulates cell shape and orientation during gonad morphogenesisAbl interactor 1 promotes tyrosine 296 phosphorylation of mammalian enabled (Mena) by c-Abl kinaseReceptor protein tyrosine phosphatases in nervous system developmentThe beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogeneThe Abl-related gene (Arg) nonreceptor tyrosine kinase uses two F-actin-binding domains to bundle F-actinIdentification of profilin and src homology 3 domains as binding partners for Drosophila enabledc-Abl, Lamellipodin, and Ena/VASP proteins cooperate in dorsal ruffling of fibroblasts and axonal morphogenesisModulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extensionAbelson kinase acts as a robust, multifunctional scaffold in regulating embryonic morphogenesis.Target-assisted iterative screening reveals novel interactors for PSD95, Nedd4, Src, Abl and Crk proteins.Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein.Phosphorylation of Enabled by the Drosophila Abelson tyrosine kinase regulates the in vivo function and protein-protein interactions of EnabledDistinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2.Vasodilator-stimulated phosphoprotein (VASP) induces actin assembly in dendritic spines to promote their development and potentiate synaptic strength.Ena/VASP proteins have an anti-capping independent function in filopodia formation.Critical roles of phosphorylation and actin binding motifs, but not the central proline-rich region, for Ena/vasodilator-stimulated phosphoprotein (VASP) function during cell migration.Abl tyrosine kinase and its substrate Ena/VASP have functional interactions with kinesin-1.Ena/VASP proteins can regulate distinct modes of actin organization at cadherin-adhesive contacts.Using Bcr-Abl to examine mechanisms by which abl kinase regulates morphogenesis in Drosophila.Ena drives invasive macrophage migration in Drosophila embryos.Ena/VASP function in retinal axons is required for terminal arborization but not pathway navigation.Ena/VASP Enabled is a highly processive actin polymerase tailored to self-assemble parallel-bundled F-actin networks with FascinThe actin regulators Enabled and Diaphanous direct distinct protrusive behaviors in different tissues during Drosophila development.
P2860
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P2860
enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties.
description
1995 nî lūn-bûn
@nan
1995 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մարտին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
enabled, a dosage-sensitive su ...... SH3 domain-binding properties.
@ast
enabled, a dosage-sensitive su ...... SH3 domain-binding properties.
@en
type
label
enabled, a dosage-sensitive su ...... SH3 domain-binding properties.
@ast
enabled, a dosage-sensitive su ...... SH3 domain-binding properties.
@en
prefLabel
enabled, a dosage-sensitive su ...... SH3 domain-binding properties.
@ast
enabled, a dosage-sensitive su ...... SH3 domain-binding properties.
@en
P2093
P356
P1433
P1476
enabled, a dosage-sensitive su ...... SH3 domain-binding properties
@en
P2093
P304
P356
10.1101/GAD.9.5.521
P50
P577
1995-03-01T00:00:00Z