Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5α.
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Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.Primate TRIM5 proteins form hexagonal nets on HIV-1 capsids.Closing the net on retrovirusesSPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC SignalingThe TRIMendous Role of TRIMs in Virus-Host Interactions.The B-box module of CYLD is responsible for its intermolecular interaction and cytoplasmic localization.Solution NMR structure of the TRIM21 B-box2 and identification of residues involved in its interaction with the RING domain.Structure and catalytic activation of the TRIM23 RING E3 ubiquitin ligase.TRIM5α SPRY/coiled-coil interactions optimize avid retroviral capsid recognition.A general model for retroviral capsid pattern recognition by TRIM5 proteins.The three-fold axis of the HIV-1 capsid lattice is the species-specific binding interface for TRIM5α.Are Evolution and the Intracellular Innate Immune System Key Determinants in HIV Transmission?Conserved structural and functional aspects of the tripartite motif gene family point towards therapeutic applications in multiple diseases.Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21.
P2860
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P2860
Mechanism of B-box 2 domain-mediated higher-order assembly of the retroviral restriction factor TRIM5α.
description
2016 nî lūn-bûn
@nan
2016 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Mechanism of B-box 2 domain-me ...... ral restriction factor TRIM5α.
@ast
Mechanism of B-box 2 domain-me ...... ral restriction factor TRIM5α.
@en
type
label
Mechanism of B-box 2 domain-me ...... ral restriction factor TRIM5α.
@ast
Mechanism of B-box 2 domain-me ...... ral restriction factor TRIM5α.
@en
prefLabel
Mechanism of B-box 2 domain-me ...... ral restriction factor TRIM5α.
@ast
Mechanism of B-box 2 domain-me ...... ral restriction factor TRIM5α.
@en
P2093
P2860
P50
P356
P1433
P1476
Mechanism of B-box 2 domain-me ...... iral restriction factor TRIM5α
@en
P2093
Barbie K Ganser-Pornillos
Devin Christensen
Ginna Doss
Katarzyna Skorupka
Marcin D Roganowicz
Steven L Alam
Yueping Wan
P2860
P356
10.7554/ELIFE.16309
P407
P577
2016-06-02T00:00:00Z