The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.
about
Physiological, pathological, and structural implications of non-enzymatic protein-protein interactions of the multifunctional human transglutaminase 2Fibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions.Regulation of Rac1 activation by the low density lipoprotein receptor-related proteinPDGF‑stimulated dispersal of cell clusters and disruption of fibronectin matrix on three-dimensional collagen matrices requires matrix metalloproteinase-2.The LDL receptor-related protein 1 (LRP1) regulates the PDGF signaling pathway by binding the protein phosphatase SHP-2 and modulating SHP-2- mediated PDGF signaling events.LRP1 regulates remodeling of the extracellular matrix by fibroblasts.Fibronectin matrix turnover occurs through a caveolin-1-dependent process.Low density lipoprotein receptor-related protein 1 (LRP1) forms a signaling complex with platelet-derived growth factor receptor-beta in endosomes and regulates activation of the MAPK pathwayLow-density lipoprotein receptor-related protein (LRP)-mediated clearance of activated blood coagulation co-factors and proteases: clearance mechanism or regulation?Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptorPolarized traffic of LRP1 involves AP1B and SNX17 operating on Y-dependent sorting motifs in different pathways.Constitutively activated dystrophic muscle fibroblasts show a paradoxical response to TGF-beta and CTGF/CCN2.Regulation of the composition of the extracellular matrix by low density lipoprotein receptor-related protein-1: activities based on regulation of mRNA expression.LRP1b shows restricted expression in human tissues and binds to several extracellular ligands, including fibrinogen and apoE-carrying lipoproteins.Urokinase-type plasminogen activator receptor regulates a novel pathway of fibronectin matrix assembly requiring Src-dependent transactivation of epidermal growth factor receptor.Low density lipoprotein receptor-related protein 1 couples β1 integrin activation to degradation.Perindoprilat modulates the activity of lipoprotein receptor-related protein in human mesangial cells.The low density lipoprotein receptor-related protein functions as an endocytic receptor for decorin.Shedding of low-density lipoprotein receptor–related protein-1 in acute respiratory distress syndrome.LRP1 is required for novobiocin-mediated fibronectin turnoverDelayed Treatment with Plasminogen Activator Inhibitor-1 Decoys Reduces Tubulointerstitial Fibrosis
P2860
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P2860
The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.
description
2002 nî lūn-bûn
@nan
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
The low density lipoprotein re ...... accumulation on cell surfaces.
@ast
The low density lipoprotein re ...... accumulation on cell surfaces.
@en
type
label
The low density lipoprotein re ...... accumulation on cell surfaces.
@ast
The low density lipoprotein re ...... accumulation on cell surfaces.
@en
prefLabel
The low density lipoprotein re ...... accumulation on cell surfaces.
@ast
The low density lipoprotein re ...... accumulation on cell surfaces.
@en
P2093
P2860
P356
P1476
The low density lipoprotein re ...... accumulation on cell surfaces.
@en
P2093
Ana M Salicioni
Dudley K Strickland
Elena Loukinova
Irina Mikhailenko
Kellie S Mizelle
Steven L Gonias
P2860
P304
16160-16166
P356
10.1074/JBC.M201401200
P407
P577
2002-02-26T00:00:00Z