Activation of the MAPK pathway enhances sensitivity of MCF-7 breast cancer cells to the mitogenic effect of estradiol.
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Membrane estrogen receptor-alpha levels predict estrogen-induced ERK1/2 activation in MCF-7 cellsA Role for Histone H2B Variants in Endocrine-Resistant Breast Cancer.Novel cancer-targeting SPECT/NIRF dual-modality imaging probe (99m)Tc-PC-1007: synthesis and biological evaluation.Epigenetic reprogramming of HOXC10 in endocrine-resistant breast cancerMechanisms of resistance to structurally diverse antiestrogens differ under premenopausal and postmenopausal conditions: evidence from in vitro breast cancer cell models.Adaptation to estradiol deprivation causes up-regulation of growth factor pathways and hypersensitivity to estradiol in breast cancer cells.Demethylation of promoter C region of estrogen receptor alpha gene is correlated with its enhanced expression in estrogen-ablation resistant MCF-7 cells.Mechanisms of acquired resistance to endocrine therapy in hormone-dependent breast cancer cells.AroER tri-screen is a biologically relevant assay for endocrine disrupting chemicals modulating the activity of aromatase and/or the estrogen receptor.Global analysis of ligand sensitivity of estrogen inducible and suppressible genes in MCF7/BUS breast cancer cells by DNA microarrayThe molecular mechanisms underlying the pharmacological actions of ER modulators: implications for new drug discovery in breast cancer.Acquired resistance to selective estrogen receptor modulators (SERMs) in clinical practice (tamoxifen & raloxifene) by selection pressure in breast cancer cell populationsClinical instability of breast cancer markers is reflected in long-term in vitro estrogen deprivation studiesThe turnover of estrogen receptor α by the selective estrogen receptor degrader (SERD) fulvestrant is a saturable process that is not required for antagonist efficacyAn "omics" approach to determine the mechanisms of acquired aromatase inhibitor resistanceFemara and the future: tailoring treatment and combination therapies with Femara.Letrozole in the extended adjuvant setting: MA.17The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling.Aromatase overexpression induces malignant changes in estrogen receptor α negative MCF-10A cells.Crosstalk with insulin and dependence on PI3K/Akt/mTOR rather than MAPK pathways in upregulation of basal growth following long-term oestrogen deprivation in three human breast cancer cell lines.Estrogen Receptors in Cell Membranes: Regulation and Signaling.
P2860
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P2860
Activation of the MAPK pathway enhances sensitivity of MCF-7 breast cancer cells to the mitogenic effect of estradiol.
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
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2002年學術文章
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name
Activation of the MAPK pathway ...... mitogenic effect of estradiol.
@ast
Activation of the MAPK pathway ...... mitogenic effect of estradiol.
@en
type
label
Activation of the MAPK pathway ...... mitogenic effect of estradiol.
@ast
Activation of the MAPK pathway ...... mitogenic effect of estradiol.
@en
prefLabel
Activation of the MAPK pathway ...... mitogenic effect of estradiol.
@ast
Activation of the MAPK pathway ...... mitogenic effect of estradiol.
@en
P2093
P356
P1433
P1476
Activation of the MAPK pathway ...... mitogenic effect of estradiol.
@en
P2093
Ji-Ping Wang
Mark Conaway
Richard J Santen
Shigeru Masamura
P304
P356
10.1210/EN.2002-220186
P407
P577
2002-09-01T00:00:00Z