Epidermal growth factor receptor-dependent and -independent cell-signaling pathways originating from the urokinase receptor.
about
uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180.Urokinase receptor and resistance to targeted anticancer agentsVEGF-initiated angiogenesis and the uPA/uPAR systemHER2 and uPAR cooperativity contribute to metastatic phenotype of HER2-positive breast cancerThe urokinase receptor (uPAR) and the uPAR-associated protein (uPARAP/Endo180): membrane proteins engaged in matrix turnover during tissue remodelingSoluble urokinase-type plasminogen activator receptor inhibits cancer cell growth and invasion by direct urokinase-independent effects on cell signaling.Epidermal growth factor receptor translocation to the mitochondria: regulation and effect.uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells.uPAR-induced cell adhesion and migration: vitronectin provides the keyTyrosine-kinase inhibition results in EGFR clustering at focal adhesions and consequent exocytosis in uPAR down-regulated cells of head and neck cancers.Number and brightness image analysis reveals ATF-induced dimerization kinetics of uPAR in the cell membraneThe Kruppel-like KLF4 transcription factor, a novel regulator of urokinase receptor expression, drives synthesis of this binding site in colonic crypt luminal surface epithelial cells.Clathrin and LRP-1-independent constitutive endocytosis and recycling of uPAR.Hepatocyte growth factor (HGF) modulates GABAergic inhibition and seizure susceptibility.Low density lipoprotein receptor-related protein (LRP1) regulates Rac1 and RhoA reciprocally to control Schwann cell adhesion and migration.uPAR/cathepsin B overexpression reverse angiogenesis by rescuing FAK phosphorylation in uPAR/cathepsin B down regulated meningioma.Factor XII stimulates ERK1/2 and Akt through uPAR, integrins, and the EGFR to initiate angiogenesis.The urokinase receptor supports tumorigenesis of human malignant pleural mesothelioma cells.Functional convergence of signalling by GPI-anchored and anchorless forms of a salamander protein implicated in limb regeneration.Heat shock proteins HSP70 and MRJ cooperatively regulate cell adhesion and migration through urokinase receptor.Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cellsExtensive crosstalk between O-GlcNAcylation and phosphorylation regulates Akt signaling.Decreased Mitogen Inducible Gene 6 (MIG-6) Associated with Symptom Severity in Children with Autism.Protein kinase Cgamma regulates myosin IIB phosphorylation, cellular localization, and filament assemblySpecific interference of urokinase-type plasminogen activator receptor and matrix metalloproteinase-9 gene expression induced by double-stranded RNA results in decreased invasion, tumor growth, and angiogenesis in gliomas.Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells.Mechanism of p27 upregulation induced by downregulation of cathepsin B and uPAR in gliomaA transformation in the mechanism by which the urokinase receptor signals provides a selection advantage for estrogen receptor-expressing breast cancer cells in the absence of estrogenAlternative signaling pathways: when, where and why?Role of urokinase receptor in tumor progression and development.Dietary chemopreventative benzyl isothiocyanate inhibits breast cancer stem cells in vitro and in vivo.Reversibility of epithelial-mesenchymal transition (EMT) induced in breast cancer cells by activation of urokinase receptor-dependent cell signaling.Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasisTransforming growth factor-Beta and urokinase-type plasminogen activator: dangerous partners in tumorigenesis-implications in skin cancer.Involvement of urokinase-type plasminogen activator system in cancer: an overview.Pilot study of a novel combination of two therapeutic vaccines in advanced non-small-cell lung cancer patients.Urokinase is a negative modulator of Egf-dependent proliferation and motility in the two breast cancer cell lines MCF-7 and MDA-MB-231.Expression of matrix macromolecules and functional properties of EGF-responsive colon cancer cells are inhibited by panitumumab.The C11R gene, which encodes the vaccinia virus growth factor, is partially responsible for MVA-induced NF-κB and ERK2 activation.Human sprouty1 suppresses urokinase receptor-stimulated cell migration and invasion.
P2860
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P2860
Epidermal growth factor receptor-dependent and -independent cell-signaling pathways originating from the urokinase receptor.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Epidermal growth factor recept ...... g from the urokinase receptor.
@ast
Epidermal growth factor recept ...... g from the urokinase receptor.
@en
type
label
Epidermal growth factor recept ...... g from the urokinase receptor.
@ast
Epidermal growth factor recept ...... g from the urokinase receptor.
@en
prefLabel
Epidermal growth factor recept ...... g from the urokinase receptor.
@ast
Epidermal growth factor recept ...... g from the urokinase receptor.
@en
P2093
P356
P1476
Epidermal growth factor recept ...... g from the urokinase receptor.
@en
P2093
Denise M O'Donnell
Keena S Thomas
Steven L Gonias
P304
P356
10.1074/JBC.M210877200
P407
P577
2002-11-07T00:00:00Z