Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM.
about
Atomic Resolution Structure of Monomorphic Aβ42 Amyloid FibrilsCryo-EM reveals the steric zipper structure of a light chain-derived amyloid fibrilDeducing the symmetry of helical assemblies: Applications to membrane proteins.Molecular architecture of Aβ fibrils grown in cerebrospinal fluid solution and in a cell culture model of Aβ plaque formation.Atomic-resolution structure of a disease-relevant Aβ(1-42) amyloid fibril.A new structural model of Alzheimer's Aβ42 fibrils based on electron paramagnetic resonance data and Rosetta modelingElectron tomography reveals the fibril structure and lipid interactions in amyloid deposits.Specific Binding of Cu(II) Ions to Amyloid-Beta Peptides Bound to Aggregation-Inhibiting Molecules or SDS Micelles Creates Complexes that Generate Radical Oxygen Species.Quenched hydrogen-deuterium exchange NMR of a disease-relevant Aβ(1-42) amyloid polymorphStudy of structural stability and damaging effect on membrane for four Aβ42 dimers.Amino acid substitutions [K16A] and [K28A] distinctly affect amyloid β-protein oligomerization.Implications for Alzheimer's disease of an atomic resolution structure of amyloid-β(1-42) fibrils.Amyloid structure exhibits polymorphism on multiple length scales in human brain tissue.Amyloid plaque structure and cell surface interactions of β-amyloid fibrils revealed by electron tomography.Chiral recognition in amyloid fiber growth.The activities of amyloids from a structural perspective.HP-β-cyclodextrin as an inhibitor of amyloid-β aggregation and toxicity.Polymorphism of Amyloid Fibrils In Vivo.Ring-like N-fold Models of Aβ42 fibrils.Cryo-EM structures of tau filaments from Alzheimer's disease.Protein folding, misfolding and aggregation: The importance of two-electron stabilizing interactions.Identification of key regions and residues controlling Aβ folding and assembly.A critical role for the self-assembly of Amyloid-β1-42 in neurodegeneration.Cross-seeding between Aβ40 and Aβ42 in Alzheimer's disease.APP/Aβ structural diversity and Alzheimer's disease pathogenesis.Probing oligomerization of amyloid beta peptide in silico.Hydrodynamic effects on β-amyloid (16-22) peptide aggregation.The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril.Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer's disease.Insights into protein misfolding and aggregation enabled by solid-state NMR spectroscopy.Amyloid fibril polymorphism - a challenge for molecular imaging and therapy.Fibril structure of amyloid-β(1-42) by cryo-electron microscopy.Suppression of Oligomer Formation and Formation of Non-Toxic Fibrils upon Addition of Mirror-Image Aβ42 to the Natural l-Enantiomer.Out-of-Register Aβ42 Assemblies as Models for Neurotoxic Oligomers and Fibrils.Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp.Covalent Tethering and Residues with Bulky Hydrophobic Side Chains Enable Self-Assembly of Distinct Amyloid Structures.Physical basis of amyloid fibril polymorphism.Conformational Dynamics and Stability of U-Shaped and S-Shaped Amyloid β Assemblies.Elastic moduli of biological fibers in a coarse-grained model: crystalline cellulose and β-amyloids.Structural Characterization of Monomers and Oligomers of D-Amino Acid-Containing Peptides Using T-Wave Ion Mobility Mass Spectrometry.
P2860
Q27714742-CDC7E836-0E08-44F9-97DD-046133DEBE8BQ28828663-604960FD-2E29-4146-8669-820536637E0EQ30152776-C3461426-F329-4FE1-886B-7E09DCDF3EBCQ30315437-014BBE07-73C5-41BD-91C6-EC1697037B90Q30391127-09249297-2058-4E9F-B599-AAE1C39D597BQ31041418-4DA17CE7-8009-49FC-9E3F-F7E593E7D013Q36007352-F3CCEBFF-4D64-4D51-8FF0-FE4B4BEAAAA9Q36115161-407ED0F9-66BF-4232-836E-F13BD37E910DQ36314605-B1B6322D-61D4-4E11-85F4-588BF67FFBB8Q36395898-B1336558-A413-4747-AC02-627C5EF76ECAQ37088713-72FE6A13-D53D-4BD4-8B2B-0ED691CBD12EQ37213771-255FF1C0-35AC-402A-884A-DCF794FD856BQ37257552-C40929D6-B5F4-4660-85FE-DAE3418A459EQ37668087-6810E78D-7B7F-41D8-9871-9D2D999D2B3BQ38901646-539CB875-91C4-46B4-AFF3-E689EF6437BBQ39004351-6F8274F8-B763-4DD8-AB12-6FC5189DCEC6Q39609556-08A8B879-F50B-48C2-B9CB-9CD103E0D3F2Q39939213-EB933135-1C5B-4E8C-B60F-04D420EBCA4CQ41140452-8B8A29B6-87D2-49C3-8B08-0D4E7C0AB4CEQ41597304-48EAD26F-A1FD-40BF-861E-D2036FF11F0EQ41702344-1658BE90-6472-4C7F-8CD5-9509836DF475Q42094428-80F9AC49-AD7F-4F12-8A1C-16E8B9415AA5Q42408339-72F826E9-9744-4B4A-AD3F-B645046EB688Q44369500-7434EA9D-CFB5-4E21-85E3-B8CD43B48378Q46320596-EF2C6967-7D3F-4033-8BB2-CBC179B44FDDQ46460031-9846BAF9-A5A9-47DC-904B-FC90A77C9E3AQ46512456-445D37A5-68B9-4978-BB42-B8266F0D53DEQ46519937-55E16CB8-3497-4A8D-AD39-B06699DE14B2Q47381323-B8A610CC-0017-49F9-A8AB-A1F09D649FDAQ47647902-8B14E08B-7468-438A-B631-CDF73CAFA6D5Q47717455-ED9671D1-670B-455A-9853-F7E105E2697BQ47838176-BFEEFA74-7527-4A41-8DEC-31F4BDD9E856Q47953656-5CA4B799-763D-4812-90B6-4A682BB6EA6DQ48193574-EFC96F45-BBF0-465A-B666-FADEF6B5AFC1Q48239663-2FF08FC1-5619-4BDA-B98F-5973DABEDC91Q48314753-2FB6B13C-7ADE-41EA-B4D4-D211CDE6F5DAQ49913157-FF8EEAB8-B818-4A40-A4E1-FA2E6EC94751Q50002268-0C209B09-E5C1-4A18-B7BB-C1F1368AF9C1Q50097852-3BAACD20-8C54-4301-A5F0-C9FC89E33F3DQ51339440-2E235BD4-7687-4125-8CDD-791436D13EFC
P2860
Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM.
description
2015 nî lūn-bûn
@nan
2015 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM.
@ast
Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM.
@en
type
label
Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM.
@ast
Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM.
@en
prefLabel
Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM.
@ast
Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM.
@en
P2093
P2860
P50
P356
P1476
Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM.
@en
P2093
Alexis Rohou
Keren Lasker
Marcus Fändrich
Matthias Schmidt
P2860
P304
11858-11863
P356
10.1073/PNAS.1503455112
P407
P577
2015-09-08T00:00:00Z