Reduced sialylation status in UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE)-deficient mice.
about
Genes associated with MUC5AC expression in small airway epithelium of human smokers and non-smokersGNE is involved in the early development of skeletal and cardiac muscleSialic acid utilisation and synthesis in the neonatal rat revisitedGanglioside GM3 levels are altered in a mouse model of HIBM: GM3 as a cellular marker of the disease.UDP-GlcNAc 2-Epimerase/ManNAc Kinase (GNE): A Master Regulator of Sialic Acid Synthesis.Sialylation and muscle performance: sialic acid is a marker of muscle ageing.GNE myopathy: current update and future therapy.Quantitative hydrophilic interaction chromatography-mass spectrometry analysis of N-acetylneuraminic acid and N-acetylmannosamine in human plasma.Substantial deficiency of free sialic acid in muscles of patients with GNE myopathy and in a mouse modelExperimental approaches to interfere with the polysialylation of the neural cell adhesion molecule in vitro and in vivo.Safety and in vivo expression of a GNE-transgene: a novel treatment approach for hereditary inclusion body myopathy-2.Regulation and pathophysiological implications of UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE) as the key enzyme of sialic acid biosynthesis.Hereditary Inclusion Body Myopathy (HIBM2)Increased amyloid β-peptide uptake in skeletal muscle is induced by hyposialylation and may account for apoptosis in GNE myopathy.The key enzyme of the sialic acid metabolism is involved in embryoid body formation and expression of marker genes of germ layer formation.Gne depletion during zebrafish development impairs skeletal muscle structure and function.CDG Therapies: From Bench to Bedside.Function and Mutations of the GNE Gene Leading to Distal Myopathy with Rimmed Vacuoles/Hereditary Inclusion-Body Myopathy, Animal Models, and Potential TreatmentGNE Myopathy with Prominent Axial Muscle Involvement
P2860
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P2860
Reduced sialylation status in UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE)-deficient mice.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Reduced sialylation status in ...... e kinase (GNE)-deficient mice.
@ast
Reduced sialylation status in ...... e kinase (GNE)-deficient mice.
@en
type
label
Reduced sialylation status in ...... e kinase (GNE)-deficient mice.
@ast
Reduced sialylation status in ...... e kinase (GNE)-deficient mice.
@en
prefLabel
Reduced sialylation status in ...... e kinase (GNE)-deficient mice.
@ast
Reduced sialylation status in ...... e kinase (GNE)-deficient mice.
@en
P2093
P1476
Reduced sialylation status in ...... e kinase (GNE)-deficient mice.
@en
P2093
André Orthmann
Daniel Gagiannis
Ilona Danssmann
Martina Schwarzkopf
Rüdiger Horstkorte
Wenke Weidemann
P2888
P304
P356
10.1007/S10719-006-9019-7
P577
2007-01-19T00:00:00Z
P6179
1035348846