about
Characterization and therapeutic potential of induced pluripotent stem cell-derived cardiovascular progenitor cellsTranscriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cellsThe "lnc" between 3D chromatin structure and X chromosome inactivationThe roles of the reprogramming factors Oct4, Sox2 and Klf4 in resetting the somatic cell epigenome during induced pluripotent stem cell generationConcise review: Pluripotency and the transcriptional inactivation of the female Mammalian X chromosomeA bivalent chromatin structure marks key developmental genes in embryonic stem cellsBiP acts as a molecular ratchet during posttranslational transport of prepro-alpha factor across the ER membrane.Protein transport by purified yeast Sec complex and Kar2p without membranes.Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motifPolycomb complexes repress developmental regulators in murine embryonic stem cellsRole of histone H3 lysine 27 methylation in X inactivationDirectly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contributionCharacterization of the proline-rich region of mouse MAPKAP kinase 2: influence on catalytic properties and binding to the c-abl SH3 domain in vitro.The MAP kinase-activated protein kinase 2 contains a proline-rich SH3-binding domain.Post-translational regulation of Oct4 transcriptional activitySigned weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells.Genome-wide dynamics of replication timing revealed by in vitro models of mouse embryogenesis.Identification of context-dependent motifs by contrasting ChIP binding data.Posttranslational protein translocation across the membrane of the endoplasmic reticulum.Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineagesThe Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation.The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome.The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline MemoryFemale human iPSCs retain an inactive X chromosome.Xist RNA and the mechanism of X chromosome inactivation.Generation of human induced pluripotent stem cells from dermal fibroblastsHighly efficient large-scale lentiviral vector concentration by tandem tangential flow filtration.Interactions between Sec complex and prepro-alpha-factor during posttranslational protein transport into the endoplasmic reticulumMechanistic insights into reprogramming to induced pluripotency.X chromosome reactivation dynamics reveal stages of reprogramming to pluripotencyDerivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells.Reprogramming to pluripotency: stepwise resetting of the epigenetic landscapeMediator coordinates PIC assembly with recruitment of CHD1Derivation of new human embryonic stem cell lines reveals rapid epigenetic progression in vitro that can be prevented by chemical modification of chromatin.Progress in understanding reprogramming to the induced pluripotent stateRole of the murine reprogramming factors in the induction of pluripotencyMolecular analyses of human induced pluripotent stem cells and embryonic stem cells.A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2'-dC upon inhibition of ribonucleotide reductase.Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome.
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Kathrin Plath
@ast
Kathrin Plath
@en
Kathrin Plath
@es
Kathrin Plath
@fr
Kathrin Plath
@nl
Kathrin Plath
@sl
type
label
Kathrin Plath
@ast
Kathrin Plath
@en
Kathrin Plath
@es
Kathrin Plath
@fr
Kathrin Plath
@nl
Kathrin Plath
@sl
prefLabel
Kathrin Plath
@ast
Kathrin Plath
@en
Kathrin Plath
@es
Kathrin Plath
@fr
Kathrin Plath
@nl
Kathrin Plath
@sl
P106
P21
P31
P496
0000-0001-7796-3372