Engineered vaginal lactobacillus strain for mucosal delivery of the human immunodeficiency virus inhibitor cyanovirin-N
about
Engineering of Lactobacillus jensenii to secrete RANTES and a CCR5 antagonist analogue as live HIV-1 blockersAdvances in HIV microbicide developmentMicrobicides: a new hope for HIV preventionDesigned oligomers of cyanovirin-N show enhanced HIV neutralizationEscherichia coli surface display of single-chain antibody VRC01 against HIV-1 infection.Development of an HIV-1 Microbicide Based on Caulobacter crescentus: Blocking Infection by High-Density Display of Virus Entry Inhibitors.A review of current intravaginal drug delivery approaches employed for the prophylaxis of HIV/AIDS and prevention of sexually transmitted infectionsThe superior folding of a RANTES analogue expressed in lactobacilli as compared to mammalian cells reveals a promising system to screen new RANTES mutants.sCD4-17b bifunctional protein: extremely broad and potent neutralization of HIV-1 Env pseudotyped viruses from genetically diverse primary isolates.Development of an HIV-1 specific microbicide using Caulobacter crescentus S-layer mediated display of CD4 and MIP1alphaHistorical development of vaginal microbicides to prevent sexual transmission of HIV in women: from past failures to future hopes.Antiviral lectins as potential HIV microbicidesCommensal bacteria modulate innate immune responses of vaginal epithelial cell multilayer culturesPrevention of vaginal SHIV transmission in macaques by a live recombinant Lactobacillus.In vivo evaluation of safety and toxicity of a Lactobacillus jensenii producing modified cyanovirin-N in a rhesus macaque vaginal challenge modelHomeostatic properties of Lactobacillus jensenii engineered as a live vaginal anti-HIV microbicidePreventing mucosal HIV transmission with topical microbicides: challenges and opportunities.Vaginal microbiota and its role in HIV transmission and infection.Robust vaginal colonization of macaques with a novel vaginally disintegrating tablet containing a live biotherapeutic product to prevent HIV infection in women.A Chinese rhesus macaque (Macaca mulatta) model for vaginal Lactobacillus colonization and live microbicide development.The lectins griffithsin, cyanovirin-N and scytovirin inhibit HIV-1 binding to the DC-SIGN receptor and transfer to CD4(+) cells.Demonstration of vaginal colonization with GusA-expressing Lactobacillus jensenii following oral delivery in rhesus macaques.Carbohydrate-binding agents: a potential future cornerstone for the chemotherapy of enveloped viruses?Rational design of novel HIV-1 entry inhibitors by RANTES engineeringEngineering of a human vaginal Lactobacillus strain for surface expression of two-domain CD4 moleculesRhizosecretion improves the production of Cyanovirin-N in Nicotiana tabacum through simplified downstream processingTopical application of entry inhibitors as "virustats" to prevent sexual transmission of HIV infection.Mucosal delivery of therapeutic and prophylactic molecules using lactic acid bacteria.Vaginal drug delivery systems for HIV prevention.Non-Antiretroviral Microbicides for HIV Prevention.Expression of Human Immunodeficiency Virus Type 1 Neutralizing Antibody Fragments Using Human Vaginal Lactobacillus.Mucosal Lactobacillus vectored vaccines.Potential of carbohydrate-binding agents as therapeutics against enveloped viruses.Engineering antibiotic production and overcoming bacterial resistance.Bio-inspired, bioengineered and biomimetic drug delivery carriers.Lectins with anti-HIV activity: a review.Human lectins and their roles in viral infections.Bioengineered probiotics as a new hope for health and diseases: an overview of potential and prospects.The Tetrameric Plant Lectin BanLec Neutralizes HIV through Bidentate Binding to Specific Viral Glycans.Cyanovirin-N produced in rice endosperm offers effective pre-exposure prophylaxis against HIV-1BaL infection in vitro.
P2860
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P2860
Engineered vaginal lactobacillus strain for mucosal delivery of the human immunodeficiency virus inhibitor cyanovirin-N
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Engineered vaginal lactobacill ...... y virus inhibitor cyanovirin-N
@ast
Engineered vaginal lactobacill ...... y virus inhibitor cyanovirin-N
@en
type
label
Engineered vaginal lactobacill ...... y virus inhibitor cyanovirin-N
@ast
Engineered vaginal lactobacill ...... y virus inhibitor cyanovirin-N
@en
prefLabel
Engineered vaginal lactobacill ...... y virus inhibitor cyanovirin-N
@ast
Engineered vaginal lactobacill ...... y virus inhibitor cyanovirin-N
@en
P2093
P2860
P356
P1476
Engineered vaginal lactobacill ...... y virus inhibitor cyanovirin-N
@en
P2093
Courtney L Frazier-Parker
Daniel Tsai
David A Simpson
Dean H Hamer
Kirsten P Essenmacher
Laurel A Lagenaur
Srinivas S Rao
Thomas P Parks
Xiaowen Liu
P2860
P304
P356
10.1128/AAC.00493-06
P407
P50
P577
2006-10-01T00:00:00Z