Microneedle delivery of an M2e-TLR5 ligand fusion protein to skin confers broadly cross-protective influenza immunity
about
Effect of vaccine administration modality on immunogenicity and efficacy.Universal influenza vaccines, a dream to be realized soon.Microneedle delivery of trivalent influenza vaccine to the skin induces long-term cross-protection.Consensus M2e peptide conjugated to gold nanoparticles confers protection against H1N1, H3N2 and H5N1 influenza A viruses.Tetanus toxin fragment C fused to flagellin makes a potent mucosal vaccine.Protection against Influenza A Virus Challenge with M2e-Displaying Filamentous Escherichia coli Phages.Microneedle patch delivery to the skin of virus-like particles containing heterologous M2e extracellular domains of influenza virus induces broad heterosubtypic cross-protection.The role of microneedles for drug and vaccine delivery.Membrane-anchored CCL20 augments HIV Env-specific mucosal immune responses.Biomedical applications of microneedles in therapeutics: recent advancements and implications in drug delivery.A boosting skin vaccination with dissolving microneedle patch encapsulating M2e vaccine broadens the protective efficacy of conventional influenza vaccines.Microneedles for vaccine delivery: challenges and future perspectives.Mucosal vaccine delivery: Current state and a pediatric perspectiveEnhancing vaccine effectiveness with delivery technology.The success of microneedle-mediated vaccine delivery into skin.Dry influenza vaccines: towards a stable, effective and convenient alternative to conventional parenteral influenza vaccination.From Variation of Influenza Viral Proteins to Vaccine Development.Protein nanoparticle vaccine based on flagellin carrier fused to influenza conserved epitopes confers full protection against influenza A virus challenge.Conjugation of wildtype and hypoallergenic mugwort allergen Art v 1 to flagellin induces IL-10-DC and suppresses allergen-specific TH2-responses in vivo.Double-layered protein nanoparticles induce broad protection against divergent influenza A viruses.Cutaneous vaccination with coated microneedles prevents development of airway allergy.Flagellin-fused protein targeting M2e and HA2 induces potent humoral and T-cell responses and protects mice against various influenza viruses a subtypes.Mini-Review: Assessing the Potential Impact of Microneedle Technologies on Home Healthcare Applications.Heterosubtypic influenza protection elicited by double-layered polypeptide nanoparticles in miceCombination of M2e peptide with stalk HA epitopes of influenza A virus enhances protective properties of recombinant vaccineEnhanced Immune Responses Conferring Cross-Protection by Skin Vaccination With a Tri-Component Influenza Vaccine Using a Microneedle Patch
P2860
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P2860
Microneedle delivery of an M2e-TLR5 ligand fusion protein to skin confers broadly cross-protective influenza immunity
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Microneedle delivery of an M2e ...... -protective influenza immunity
@ast
Microneedle delivery of an M2e ...... -protective influenza immunity
@en
type
label
Microneedle delivery of an M2e ...... -protective influenza immunity
@ast
Microneedle delivery of an M2e ...... -protective influenza immunity
@en
prefLabel
Microneedle delivery of an M2e ...... -protective influenza immunity
@ast
Microneedle delivery of an M2e ...... -protective influenza immunity
@en
P2093
P2860
P1476
Microneedle delivery of an M2e ...... -protective influenza immunity
@en
P2093
Bao-Zhong Wang
Changbo Ou
Harvinder S Gill
Mark R Prausnitz
Richard W Compans
Ying-Chun Wang
P2860
P356
10.1016/J.JCONREL.2014.01.002
P407
P577
2014-01-11T00:00:00Z