Emerging Computational Methods for the Rational Discovery of Allosteric Drugs.

Emerging Computational Methods for the Rational Discovery of Allosteric Drugs.

Item
http://www.wikidata.org/entity/Q30358225
Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations.Allosteric cross-talk in chromatin can mediate drug-drug synergy.Identification of type I and type II inhibitors of c-Yes kinase using in silico and experimental techniques.Markov models of the apo-MDM2 lid region reveal diffuse yet two-state binding dynamics and receptor poses for computational docking.Chirality-induced spin polarization places symmetry constraints on biomolecular interactionsThe electron's spin and molecular chirality - how are they related and how do they affect life processes?Natural product analogues: towards a blueprint for analogue-focused synthesis.Toward Understanding "the Ways" of Allosteric DrugsRational Design of Selective Allosteric Inhibitors of PHGDH and Serine Synthesis with Anti-tumor Activity.Allosteric Modulation of Intact γ-Secretase Structural Dynamics.Perspectives on the discovery of NOTCH2-specific inhibitors.Engineered control of enzyme structural dynamics and function.AlloFinder: a strategy for allosteric modulator discovery and allosterome analyses.Surface Probing by Fragment-Based Screening and Computational Methods Identifies Ligandable Pockets on the von Hippel-Lindau (VHL) E3 Ubiquitin LigaseConstructing Markov State Models to elucidate the functional conformational changes of complex biomolecules
P2860

Emerging Computational Methods for the Rational Discovery of Allosteric Drugs.

Item
http://www.wikidata.org/entity/Q30358225
description
2016 nî lūn-bûn
@nan
2016 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Emerging Computational Methods for the Rational Discovery of Allosteric Drugs.
@ast
Emerging Computational Methods for the Rational Discovery of Allosteric Drugs.
@en
type
label
Emerging Computational Methods for the Rational Discovery of Allosteric Drugs.
@ast
Emerging Computational Methods for the Rational Discovery of Allosteric Drugs.
@en
prefLabel
Emerging Computational Methods for the Rational Discovery of Allosteric Drugs.
@ast
Emerging Computational Methods for the Rational Discovery of Allosteric Drugs.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P921
P932
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P1433
P1476
Emerging Computational Methods for the Rational Discovery of Allosteric Drugs.
@en
P2093
P2860
P304
P31
P356
10.1021/ACS.CHEMREV.5B00631
P433
P478
P50
P577
P698
P921
P932