Recent progress in designing inhibitors that target the drug-resistant M2 proton channels from the influenza A viruses.
about
Stereoselective synthesis of novel adamantane derivatives with high potency against rimantadine-resistant influenza A virus strains.Discovery of Highly Potent Inhibitors Targeting the Predominant Drug-Resistant S31N Mutant of the Influenza A Virus M2 Proton Channel.Influenza A Virus Nucleoprotein: A Highly Conserved Multi-Functional Viral Protein as a Hot Antiviral Drug Target.Chemical Genomics Approach Leads to the Identification of Hesperadin, an Aurora B Kinase Inhibitor, as a Broad-Spectrum Influenza Antiviral.Discovery of dapivirine, a nonnucleoside HIV-1 reverse transcriptase inhibitor, as a broad-spectrum antiviral against both influenza A and B viruses.The hydrophobic side chain of oseltamivir influences type A subtype selectivity of neuraminidase inhibitors.Design and expeditious synthesis of organosilanes as potent antivirals targeting multidrug-resistant influenza A viruses.Slow but Steady Wins the Race: Dissimilarities among New Dual Inhibitors of the Wild-Type and the V27A Mutant M2 Channels of Influenza A Virus.Expeditious Lead Optimization of Isoxazole-Containing Influenza A Virus M2-S31N Inhibitors Using the Suzuki-Miyaura Cross-Coupling Reaction.An M2-V27A channel blocker demonstrates potent in vitro and in vivo antiviral activities against amantadine-sensitive and -resistant influenza A viruses.Discovery of Potent Antivirals against Amantadine-Resistant Influenza A Viruses by Targeting the M2-S31N Proton Channel.Discovery of cyclosporine A and its analogs as broad-spectrum anti-influenza drugs with a high in vitro genetic barrier of drug resistancePharmacological Characterization of the Spectrum of Antiviral Activity and Genetic Barrier to Drug Resistance of M2-S31N Channel Blockers.Isocyanides as Influenza A Virus Subtype H5N1 Wild-Type M2 Channel Inhibitors.Exploring Ugi-Azide Four-Component Reaction Products for Broad-Spectrum Influenza Antivirals with a High Genetic Barrier to Drug Resistance.Profiling the in vitro drug-resistance mechanism of influenza A viruses towards the AM2-S31N proton channel blockers.Symmetric dimeric adamantanes for exploring the structure of two viroporins: influenza virus M2 and hepatitis C virus p7.
P2860
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P2860
Recent progress in designing inhibitors that target the drug-resistant M2 proton channels from the influenza A viruses.
description
2015 nî lūn-bûn
@nan
2015 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Recent progress in designing i ...... from the influenza A viruses.
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Recent progress in designing i ...... from the influenza A viruses.
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type
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Recent progress in designing i ...... from the influenza A viruses.
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Recent progress in designing i ...... from the influenza A viruses.
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Recent progress in designing i ...... from the influenza A viruses.
@ast
Recent progress in designing i ...... from the influenza A viruses.
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P356
P1433
P1476
Recent progress in designing i ...... from the influenza A viruses.
@en
P2093
P304
P356
10.1002/BIP.22623
P50
P577
2015-07-01T00:00:00Z