Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus
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Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genesRole of Autophagy and Apoptosis in the Postinfluenza Bacterial PneumoniaAvian Influenza Viruses, Inflammation, and CD8(+) T Cell ImmunitySystems biology from virus to humansUse of ex vivo and in vitro cultures of the human respiratory tract to study the tropism and host responses of highly pathogenic avian influenza A (H5N1) and other influenza virusesSystems approaches to influenza-virus host interactions and the pathogenesis of highly virulent and pandemic virusesPathogenicity of pandemic H1N1 influenza A virus in immunocompromised cynomolgus macaquesLocally Produced IL-10 Limits Cutaneous Vaccinia Virus SpreadMacrophage-expressed IFN-β contributes to apoptotic alveolar epithelial cell injury in severe influenza virus pneumoniaInfluenza A Virus Challenge Models in Cynomolgus Macaques Using the Authentic Inhaled Aerosol and Intra-Nasal Routes of InfectionProtection against H5N1 highly pathogenic avian and pandemic (H1N1) 2009 influenza virus infection in cynomolgus monkeys by an inactivated H5N1 whole particle vaccineCross-reactive T cells are involved in rapid clearance of 2009 pandemic H1N1 influenza virus in nonhuman primatesRespiratory viral infections and host responses; insights from genomicsDisease-promoting effects of type I interferons in viral, bacterial, and coinfectionsInfluenza virus activation of the interferon systemNanobodies with in vitro neutralizing activity protect mice against H5N1 influenza virus infectionA review of mathematical models of influenza A infections within a host or cell culture: lessons learned and challenges aheadGene expression signature-based screening identifies new broadly effective influenza a antiviralsInnate immune response of human alveolar macrophages during influenza A infectionIn vitro and in vivo characterization of new swine-origin H1N1 influenza virusesReplication of live attenuated cold-adapted H2N2 influenza virus vaccine candidates in non human primates.Closely related influenza viruses induce contrasting respiratory tract immunopathologyAfrican green monkeys recapitulate the clinical experience with replication of live attenuated pandemic influenza virus vaccine candidates.Cytokine Expression at Different Stages of Influenza A(H1N1)pdm09 Virus Infection in the Porcine Lung, Using Laser Capture Microdissection.Disease severity is associated with differential gene expression at the early and late phases of infection in nonhuman primates infected with different H5N1 highly pathogenic avian influenza virusesInfluenza virus A/Anhui/1/2013 (H7N9) replicates efficiently in the upper and lower respiratory tracts of cynomolgus macaques.The use of nonhuman primates in research on seasonal, pandemic and avian influenza, 1893-2014.Pandemic Swine-Origin H1N1 Influenza Virus Replicates to Higher Levels and Induces More Fever and Acute Inflammatory Cytokines in Cynomolgus versus Rhesus Monkeys and Can Replicate in Common Marmosets.Mast cells and influenza a virus: association with allergic responses and beyond.Confronting the next influenza pandemic with anti-inflammatory and immunomodulatory agents: why they are needed and how they might work.Correlation between Virus Replication and Antibody Responses in Macaques following Infection with Pandemic Influenza A Virus.Newcastle disease virus-vectored vaccines expressing the hemagglutinin or neuraminidase protein of H5N1 highly pathogenic avian influenza virus protect against virus challenge in monkeys.Differential Immune Profiles in Two Pandemic Influenza A(H1N1)pdm09 Virus Waves at Pandemic Epicenter.Animal models for the preclinical evaluation of candidate influenza vaccines.Translational research on influenza virus infection using a nonhuman primate model.microRNAs Regulate Host Immune Response and Pathogenesis During Influenza Infection in Rhesus Macaques.Extrapulmonary tissue responses in cynomolgus macaques (Macaca fascicularis) infected with highly pathogenic avian influenza A (H5N1) virus.Lethal dissemination of H5N1 influenza virus is associated with dysregulation of inflammation and lipoxin signaling in a mouse model of infection.Host response to influenza virus: protection versus immunopathology.Pandemic 2009 H1N1 influenza virus causes diffuse alveolar damage in cynomolgus macaques.
P2860
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P2860
Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Early and sustained innate imm ...... hly pathogenic influenza virus
@ast
Early and sustained innate imm ...... hly pathogenic influenza virus
@en
type
label
Early and sustained innate imm ...... hly pathogenic influenza virus
@ast
Early and sustained innate imm ...... hly pathogenic influenza virus
@en
prefLabel
Early and sustained innate imm ...... hly pathogenic influenza virus
@ast
Early and sustained innate imm ...... hly pathogenic influenza virus
@en
P2093
P2860
P50
P356
P1476
Early and sustained innate imm ...... hly pathogenic influenza virus
@en
P2093
Airn-E Tolnay
Carol L Sabourin
Carole R Baskin
Elizabeth R Rosenzweig
James P Long
Jamie L Fornek
John A Pyles
Kaja Murali-Krishna
Lauri D Aicher
Mark S Kotur
P2860
P304
P356
10.1073/PNAS.0813234106
P407
P50
P577
2009-02-13T00:00:00Z