The effects of influenza A virus PB1-F2 protein on polymerase activity are strain specific and do not impact pathogenesis
about
Activation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and diseaseNon-avian animal reservoirs present a source of influenza A PB1-F2 proteins with novel virulence-enhancing markers.Influenza A virus infections in swine: pathogenesis and diagnosis.Molecular determinants of influenza virus pathogenesis in mice.PB1-F2 expression by the 2009 pandemic H1N1 influenza virus has minimal impact on virulence in animal modelsPB1-F2 proteins from H5N1 and 20 century pandemic influenza viruses cause immunopathology.Influenza A virus infection kinetics: quantitative data and models.Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics.Preventing and treating secondary bacterial infections with antiviral agentsThe influenza pandemic of 2009: lessons and implications.Clinical, laboratory and radiologic characteristics of 2009 pandemic influenza A/H1N1 pneumonia: primary influenza pneumonia versus concomitant/secondary bacterial pneumonia.Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species.Increased pathogenicity of a reassortant 2009 pandemic H1N1 influenza virus containing an H5N1 hemagglutininThe influenza A virus protein PB1-F2: killing two birds with one stone?Surveillance in Eastern India (2007-2009) revealed reassortment event involving NS and PB1-F2 gene segments among co-circulating influenza A subtypes.PB1-F2 Finder: scanning influenza sequences for PB1-F2 encoding RNA segmentsRestored PB1-F2 in the 2009 pandemic H1N1 influenza virus has minimal effects in swine.Molecular signatures of virulence in the PB1-F2 proteins of H5N1 influenza viruses.PB1-F2 attenuates virulence of highly pathogenic avian H5N1 influenza virus in chickens.The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein.Differential localization and function of PB1-F2 derived from different strains of influenza A virusInfluenza A virus polymerase: structural insights into replication and host adaptation mechanismsEvolution of viral proteins originated de novo by overprintingA single N66S mutation in the PB1-F2 protein of influenza A virus increases virulence by inhibiting the early interferon response in vivoKinetic characterization of PB1-F2-mediated immunopathology during highly pathogenic avian H5N1 influenza virus infectionThe influenza virus protein PB1-F2 interacts with IKKβ and modulates NF-κB signalling.Influenza virus primes mice for pneumonia from Staphylococcus aureus.Bid and Bim collaborate during induction of T cell death in persistent infection.Overlapping signals for translational regulation and packaging of influenza A virus segment 2The ubiquitination of the influenza A virus PB1-F2 protein is crucial for its biological functionImmunopathogenic and antibacterial effects of H3N2 influenza A virus PB1-F2 map to amino acid residues 62, 75, 79, and 82.Genomic Signatures for Avian H7N9 Viruses Adapting to Humans.Naturally occurring swine influenza A virus PB1-F2 phenotypes that contribute to superinfection with Gram-positive respiratory pathogensInfection of Mouse Macrophages by Seasonal Influenza Viruses Can Be Restricted at the Level of Virus Entry and at a Late Stage in the Virus Life Cycle.Strain-dependent effects of PB1-F2 of triple-reassortant H3N2 influenza viruses in swine.Full Genome Characterization of Human Influenza A/H3N2 Isolates from Asian Countries Reveals a Rare Amantadine Resistance-Conferring Mutation and Novel PB1-F2 Polymorphisms.Three amino acid changes in PB1-F2 of highly pathogenic H5N1 avian influenza virus affect pathogenicity in mallard ducks.Induction of memory cytotoxic T cells to influenza A virus and subsequent viral clearance is not modulated by PB1-F2-dependent inflammasome activation.A novel cytotoxic sequence contributes to influenza A viral protein PB1-F2 pathogenicity and predisposition to secondary bacterial infection.Current knowledge on PB1-F2 of influenza A viruses.
P2860
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P2860
The effects of influenza A virus PB1-F2 protein on polymerase activity are strain specific and do not impact pathogenesis
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The effects of influenza A vir ...... and do not impact pathogenesis
@ast
The effects of influenza A vir ...... and do not impact pathogenesis
@en
type
label
The effects of influenza A vir ...... and do not impact pathogenesis
@ast
The effects of influenza A vir ...... and do not impact pathogenesis
@en
prefLabel
The effects of influenza A vir ...... and do not impact pathogenesis
@ast
The effects of influenza A vir ...... and do not impact pathogenesis
@en
P2860
P356
P1433
P1476
The effects of influenza A vir ...... and do not impact pathogenesis
@en
P2093
Julie L McAuley
Kelly Zhang
P2860
P304
P356
10.1128/JVI.01785-09
P577
2010-01-01T00:00:00Z