An Intein-based Strategy for the Production of Tag-free Huntingtin Exon 1 Proteins Enables New Insights into the Polyglutamine Dependence of Httex1 Aggregation and Fibril Formation
about
Nanoscale studies link amyloid maturity with polyglutamine diseases onset.Proteins Containing Expanded Polyglutamine Tracts and Neurodegenerative Disease.Polyglutamine toxicity in yeast uncovers phenotypic variations between different fluorescent protein fusions.Monomeric Huntingtin Exon 1 Has Similar Overall Structural Features for Wild-Type and Pathological Polyglutamine Lengths.The 17-residue-long N terminus in huntingtin controls step-wise aggregation in solution and on membranes via different mechanisms.
P2860
An Intein-based Strategy for the Production of Tag-free Huntingtin Exon 1 Proteins Enables New Insights into the Polyglutamine Dependence of Httex1 Aggregation and Fibril Formation
description
2016 nî lūn-bûn
@nan
2016 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի մարտին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
An Intein-based Strategy for t ...... gregation and Fibril Formation
@ast
An Intein-based Strategy for t ...... gregation and Fibril Formation
@en
type
label
An Intein-based Strategy for t ...... gregation and Fibril Formation
@ast
An Intein-based Strategy for t ...... gregation and Fibril Formation
@en
prefLabel
An Intein-based Strategy for t ...... gregation and Fibril Formation
@ast
An Intein-based Strategy for t ...... gregation and Fibril Formation
@en
P2093
P2860
P356
P1476
An Intein-based Strategy for t ...... gregation and Fibril Formation
@en
P2093
Annalisa Ansaloni
John B Warner
Sophie Vieweg
Zhe-Ming Wang
P2860
P304
12074-12086
P356
10.1074/JBC.M116.713982
P407
P577
2016-03-21T00:00:00Z