Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.

Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.

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http://www.wikidata.org/entity/Q30393244
The application of tetracyclineregulated gene expression systems in the validation of novel drug targets in Mycobacterium tuberculosisExpression and Activity of the BioH Esterase of Biotin Synthesis is Independent of Genome Context.Target mechanism-based whole-cell screening identifies bortezomib as an inhibitor of caseinolytic protease in mycobacteriaFragment-based exploration of binding site flexibility in Mycobacterium tuberculosis BioA.Essential roles of methionine and S-adenosylmethionine in the autarkic lifestyle of Mycobacterium tuberculosis.A Biotin Biosynthesis Gene Restricted to Helicobacter.Mycobacterium tuberculosis in the Face of Host-Imposed Nutrient Limitation.Control of biotin biosynthesis in mycobacteria by a pyruvate carboxylase dependent metabolic signal.Hit Generation in TB Drug Discovery: From Genome to Granuloma.Targeted tumor detection: guidelines for developing biotinylated diagnostics.Structure-Based Optimization of Pyridoxal 5'-Phosphate-Dependent Transaminase Enzyme (BioA) Inhibitors that Target Biotin Biosynthesis in Mycobacterium tuberculosis.Targeting protein biotinylation enhances tuberculosis chemotherapy.Identification of Mycobacterium tuberculosis BioA inhibitors by using structure-based virtual screening.
P2860

Target-based identification of whole-cell active inhibitors of biotin biosynthesis in Mycobacterium tuberculosis.

Item
http://www.wikidata.org/entity/Q30393244
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
name
Target-based identification of ...... in Mycobacterium tuberculosis.
@ast
Target-based identification of ...... in Mycobacterium tuberculosis.
@en
type
label
Target-based identification of ...... in Mycobacterium tuberculosis.
@ast
Target-based identification of ...... in Mycobacterium tuberculosis.
@en
prefLabel
Target-based identification of ...... in Mycobacterium tuberculosis.
@ast
Target-based identification of ...... in Mycobacterium tuberculosis.
@en
P1433
P1476
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P2860
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P1433
P1476
Target-based identification of ...... in Mycobacterium tuberculosis.
@en
P2093
P2860
P304
P31
P356
10.1016/J.CHEMBIOL.2014.11.012
P433
P478
P50
P577
P698
P921
P932