Effect of D222G mutation in the hemagglutinin protein on receptor binding, pathogenesis and transmissibility of the 2009 pandemic H1N1 influenza virus
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Connecting the study of wild influenza with the potential for pandemic diseaseThe short stalk length of highly pathogenic avian influenza H5N1 virus neuraminidase limits transmission of pandemic H1N1 virus in ferretsThe soft palate is an important site of adaptation for transmissible influenza virusesReceptor specificity does not affect replication or virulence of the 2009 pandemic H1N1 influenza virus in mice and ferretsA Role for Neutrophils in Viral Respiratory Disease.Analysis of adaptation mutants in the hemagglutinin of the influenza A(H1N1)pdm09 virus.Influenza A(H1N1)pdm09 virus and asthmaPolymorphisms at residue 222 of the hemagglutinin of pandemic influenza A(H1N1)pdm09: association of quasi-species to morbidity and mortality in different risk categoriesEffects of a hemagglutinin D222G substitution on the pathogenicity of 2009 influenza A (H1N1) virus in mice.Genetic analysis of post-pandemic 2010-2011 influenza A(H1N1)pdm09 hemagglutinin virus variants that caused mild, severe, and fatal infections in Northern Greece.Molecular determinants of influenza virus pathogenesis in mice.Mutations associated with severity of the pandemic influenza A(H1N1)pdm09 in humans: a systematic review and meta-analysis of epidemiological evidence.Molecular Characterisation of the Haemagglutinin Glycan-Binding Specificity of Egg-Adapted Vaccine Strains of the Pandemic 2009 H1N1 Swine Influenza A Virus.Analysis of the Contrasting Pathogenicities Induced by the D222G Mutation in 1918 and 2009 Pandemic Influenza A VirusesReduction of Neuraminidase Activity Exacerbates Disease in 2009 Pandemic Influenza Virus-Infected Mice.Effect of serial pig passages on the adaptation of an avian H9N2 influenza virus to swine.A reassortant H9N2 influenza virus containing 2009 pandemic H1N1 internal-protein genes acquired enhanced pig-to-pig transmission after serial passages in swine.Both influenza hemagglutinin and polymerase acidic genes are important for delayed pandemic 2009 H1N1 virus clearance in the ferret model.Molecular imaging reveals a progressive pulmonary inflammation in lower airways in ferrets infected with 2009 H1N1 pandemic influenza virus.Virulence determinants of pandemic A(H1N1)2009 influenza virus in a mouse model.Phenotypic differences in virulence and immune response in closely related clinical isolates of influenza A 2009 H1N1 pandemic viruses in mice.Predominance of HA-222D/G polymorphism in influenza A(H1N1)pdm09 viruses associated with fatal and severe outcomes recently circulating in Germany.Molecular and serological investigations of the Influenza A(H1N1) 2009 pandemic virus in Turkey.Modular glycosphere assays for high-throughput functional characterization of influenza virusesH5N1 receptor specificity as a factor in pandemic riskA perspective on multiple waves of influenza pandemics.N-linked glycosylation of the hemagglutinin protein influences virulence and antigenicity of the 1918 pandemic and seasonal H1N1 influenza A viruses.Asparagine substitution at PB2 residue 701 enhances the replication, pathogenicity, and transmission of the 2009 pandemic H1N1 influenza A virus.Association analyses of large-scale glycan microarray data reveal novel host-specific substructures in influenza A virus binding glycansVirological characterization of influenza H1N1pdm09 in Vietnam, 2010-2013.In vivo evaluation of pathogenicity and transmissibility of influenza A(H1N1)pdm09 hemagglutinin receptor binding domain 222 intrahost variants isolated from a single immunocompromised patientReduced susceptibility to all neuraminidase inhibitors of influenza H1N1 viruses with haemagglutinin mutations and mutations in non-conserved residues of the neuraminidase.Role of H7 hemagglutinin in murine infectivity of influenza viruses following ocular inoculation.Clinical impact of A/H1/N1/09 influenza in patients with cirrhosis: experience from a nosocomial cluster of infection.PB2 and HA mutations increase the virulence of highly pathogenic H5N5 clade 2.3.4.4 avian influenza virus in mice.
P2860
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P2860
Effect of D222G mutation in the hemagglutinin protein on receptor binding, pathogenesis and transmissibility of the 2009 pandemic H1N1 influenza virus
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Effect of D222G mutation in th ...... pandemic H1N1 influenza virus
@ast
Effect of D222G mutation in th ...... pandemic H1N1 influenza virus
@en
type
label
Effect of D222G mutation in th ...... pandemic H1N1 influenza virus
@ast
Effect of D222G mutation in th ...... pandemic H1N1 influenza virus
@en
prefLabel
Effect of D222G mutation in th ...... pandemic H1N1 influenza virus
@ast
Effect of D222G mutation in th ...... pandemic H1N1 influenza virus
@en
P2093
P2860
P50
P921
P1433
P1476
Effect of D222G mutation in th ...... pandemic H1N1 influenza virus
@en
P2093
Akila Jayaraman
Claudia Pappas
Nancy J Cox
Rahul Raman
Ram Sasisekharan
P2860
P304
P356
10.1371/JOURNAL.PONE.0025091
P407
P577
2011-09-22T00:00:00Z