Complement is activated by IgG hexamers assembled at the cell surface. - Wikidata - wikimedia - TriplyDB

Complement is activated by IgG hexamers assembled at the cell surface.

Complement is activated by IgG hexamers assembled at the cell surface.

http://www.wikidata.org/entity/Q30409381

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Engineered IgG1-Fc--one fragment to bind them all Monoclonal antibodies targeting CD38 in hematological malignancies and beyond Complement inhibitors to treat IgM-mediated autoimmune hemolysis Human IgG4: a structural perspective The perfect storm: HLA antibodies, complement, FcγRs, and endothelium in transplant rejection Crystal structure of deglycosylated human IgG4-Fc The diverse and expanding role of mass spectrometry in structural and molecular biology The Complement System and Antibody-Mediated Transplant Rejection Global shape and ligand binding efficiency of the HIV-1-neutralizing antibodies differ from those of antibodies that cannot neutralize HIV-1 Leporid immunoglobulin G shows evidence of strong selective pressure on the hinge and CH3 domains Antibodies That Efficiently Form Hexamers upon Antigen Binding Can Induce Complement-Dependent Cytotoxicity under Complement-Limiting Conditions.CODV-Ig, a universal bispecific tetravalent and multifunctional immunoglobulin format for medical applications.Human IgG is produced in a pro-form that requires clipping of C-terminal lysines for maximal complement activation The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies.Deciphering the fine details of c1 assembly and activation mechanisms: "mission impossible"?Developing the IVIG biomimetic, hexa-Fc, for drug and vaccine applications Molecules Great and Small: The Complement System.Complement in disease: a defence system turning offensive Impact of serum immunoglobulins level and IL-18 promoter gene polymorphism among Egyptian patients with idiopathic thrombocytopenic purpura.Human IgG3 with extended half-life does not improve Fc-gamma receptor-mediated cancer antibody therapies in mice Technical Limitations of the C1q Single-Antigen Bead Assay to Detect Complement Binding HLA-Specific Antibodies.Fc-Galactosylation of Human Immunoglobulin Gamma Isotypes Improves C1q Binding and Enhances Complement-Dependent Cytotoxicity Impact of Antigen Density on the Binding Mechanism of IgG Antibodies Inhibition of the classical pathway of complement by meningococcal capsular polysaccharides IgG subclasses and allotypes: from structure to effector functions.Complement System Part I - Molecular Mechanisms of Activation and Regulation.Detection of C3d-binding donor-specific anti-HLA antibodies at diagnosis of humoral rejection predicts renal graft loss.The solution structures of two human IgG1 antibodies show conformational stability and accommodate their C1q and FcγR ligands.Prospects for engineering HIV-specific antibodies for enhanced effector function and half-life.Recent advances in renal transplantation: antibody-mediated rejection takes center stage Simultaneous determination of sample thickness, tilt, and electron mean free path using tomographic tilt images based on Beer-Lambert law.A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface.Antibody Engineering & Therapeutics, the annual meeting of The Antibody Society December 7-10, 2015, San Diego, CA, USA.Cross-reactive and pre-existing antibodies to therapeutic antibodies--Effects on treatment and immunogenicity.An Anti-C1s Monoclonal, TNT003, Inhibits Complement Activation Induced by Antibodies Against HLA Complement activation, regulation, and molecular basis for complement-related diseases Expression of factor H binding protein in meningococcal strains can vary at least 15-fold and is genetically determined.Complement inhibition prevents oncolytic vaccinia virus neutralization in immune humans and cynomolgus macaques Pre-exposure Prophylaxis With OspA-Specific Human Monoclonal Antibodies Protects Mice Against Tick Transmission of Lyme Disease Spirochetes.The role of Fc receptors in HIV prevention and therapy.

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P2860

Complement is activated by IgG hexamers assembled at the cell surface.

http://www.wikidata.org/entity/Q30409381

description

2014 nî lūn-bûn

@nan

2014 թուականի Մարտին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

@zh-hk

2014年論文

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2014年論文

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2014年论文

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name

Complement is activated by IgG hexamers assembled at the cell surface.

@ast

Complement is activated by IgG hexamers assembled at the cell surface.

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type

label

Complement is activated by IgG hexamers assembled at the cell surface.

@ast

Complement is activated by IgG hexamers assembled at the cell surface.

@en

prefLabel

Complement is activated by IgG hexamers assembled at the cell surface.

@ast

Complement is activated by IgG hexamers assembled at the cell surface.

@en

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SCIENCE.1248943

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Complement is activated by IgG hexamers assembled at the cell surface.

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Deniz Ugurlar

http://www.w3.org/2001/XMLSchema#string

Dennis R Burton

http://www.w3.org/2001/XMLSchema#string

Frank J Beurskens

http://www.w3.org/2001/XMLSchema#string

Jan G J van de Winkel

http://www.w3.org/2001/XMLSchema#string

Janine Schuurman

http://www.w3.org/2001/XMLSchema#string

Kristin Strumane

http://www.w3.org/2001/XMLSchema#string

Margaret A Lindorfer

http://www.w3.org/2001/XMLSchema#string

Marleen Voorhorst

http://www.w3.org/2001/XMLSchema#string

Piet Gros

http://www.w3.org/2001/XMLSchema#string

Ronald P Taylor

http://www.w3.org/2001/XMLSchema#string

P2860

X-ray structure of the Ca2+-binding interaction domain of C1s. Insights into the assembly of the C1 complex of complement

Crystal structure of the CUB1-EGF-CUB2 domain of human MASP-1/3 and identification of its interaction sites with mannan-binding lectin and ficolins

The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties

Crystal structure of the catalytic domain of human complement c1s: a serine protease with a handle

VADAR: a web server for quantitative evaluation of protein structure quality

Convergent solutions to binding at a protein-protein interface

Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

Structural basis of mannan-binding lectin recognition by its associated serine protease MASP-1: implications for complement activation

Structural Basis for Enhanced HIV-1 Neutralization by a Dimeric Immunoglobulin G Form of the Glycan-Recognizing Antibody 2G12

Hydration structure of a collagen peptide

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1260-1263

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scholarly article

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10.1126/SCIENCE.1248943

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6176

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343

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Albert J.R. Heck

Paul Whi Parren

Abraham J Koster

Christoph Diebolder

Ian Andrew Wilson

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2014-03-01T00:00:00Z

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260810019

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24626930

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4250092

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