Free radical stress-mediated loss of Kcnj10 protein expression in stria vascularis contributes to deafness in Pendred syndrome mouse model.
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Identification and characterization of pannexin expression in the mammalian cochleaDifferences in the pathogenicity of the p.H723R mutation of the common deafness-associated SLC26A4 gene in humans and miceProgressive irreversible hearing loss is caused by stria vascularis degeneration in an Slc26a4-insufficient mouse model of large vestibular aqueduct syndromeSlc26a4-insufficiency causes fluctuating hearing loss and stria vascularis dysfunction.Potassium ion movement in the inner ear: insights from genetic disease and mouse modelsThe role of an inwardly rectifying K(+) channel (Kir4.1) in the inner ear and hearing loss.Sudden sensorineural hearing loss and polymorphisms in iron homeostasis genes: new insights from a case-control studyImmune system of the inner ear as a novel therapeutic target for sensorineural hearing lossIntegration of human and mouse genetics reveals pendrin function in hearing and deafnessGender differences in myogenic regulation along the vascular tree of the gerbil cochlea.Function and expression pattern of nonsyndromic deafness genesFailure of fluid absorption in the endolymphatic sac initiates cochlear enlargement that leads to deafness in mice lacking pendrin expression.Epithelial cell stretching and luminal acidification lead to a retarded development of stria vascularis and deafness in mice lacking pendrin.Ephrin-B2 governs morphogenesis of endolymphatic sac and duct epithelia in the mouse inner ear.Establishment of a knock-in mouse model with the SLC26A4 c.919-2A>G mutation and characterization of its pathologyHearing loss associated with enlargement of the vestibular aqueduct: mechanistic insights from clinical phenotypes, genotypes, and mouse models.KCNJ10 may not be a contributor to nonsyndromic enlargement of vestibular aqueduct (NSEVA) in Chinese subjectsMouse model of enlarged vestibular aqueducts defines temporal requirement of Slc26a4 expression for hearing acquisitionMouse models for pendrin-associated loss of cochlear and vestibular functionSLC26A4 mutation testing for hearing loss associated with enlargement of the vestibular aqueduct.CFTR-SLC26 transporter interactions in epithelia.Caveolin-1 regulates corneal wound healing by modulating Kir4.1 activity.Regulation of ENaC-mediated sodium transport by glucocorticoids in Reissner's membrane epitheliumMutations of KCNJ10 together with mutations of SLC26A4 cause digenic nonsyndromic hearing loss associated with enlarged vestibular aqueduct syndrome.Regulation of sodium transport in the inner ear.The role of pendrin in the development of the murine inner ear.A comprehensive study of oxidative stress in sudden hearing loss.Deficiency of sphingomyelin synthase-1 but not sphingomyelin synthase-2 causes hearing impairments in mice.Reactive oxygen species in human inner ear perilymph.Intrafamilial phenotypic variability in families with biallelic SLC26A4 mutations.Functional Testing of SLC26A4 Variants-Clinical and Molecular Analysis of a Cohort with Enlarged Vestibular Aqueduct from Austria.
P2860
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P2860
Free radical stress-mediated loss of Kcnj10 protein expression in stria vascularis contributes to deafness in Pendred syndrome mouse model.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Free radical stress-mediated l ...... Pendred syndrome mouse model.
@ast
Free radical stress-mediated l ...... Pendred syndrome mouse model.
@en
type
label
Free radical stress-mediated l ...... Pendred syndrome mouse model.
@ast
Free radical stress-mediated l ...... Pendred syndrome mouse model.
@en
prefLabel
Free radical stress-mediated l ...... Pendred syndrome mouse model.
@ast
Free radical stress-mediated l ...... Pendred syndrome mouse model.
@en
P2860
P1476
Free radical stress-mediated l ...... Pendred syndrome mouse model.
@en
P2093
Philine Wangemann
Ruchira Singh
P2860
P304
P356
10.1152/AJPRENAL.00433.2007
P577
2007-10-24T00:00:00Z