Mutations in polymerase genes enhanced the virulence of 2009 pandemic H1N1 influenza virus in mice
about
Structural and Functional Characterization of K339T Substitution Identified in the PB2 Subunit Cap-binding Pocket of Influenza A VirusKey molecular factors in hemagglutinin and PB2 contribute to efficient transmission of the 2009 H1N1 pandemic influenza virusPB2-588I enhances 2009 H1N1 pandemic influenza virus virulence by increasing viral replication and exacerbating PB2 inhibition of beta interferon expression.Influenza A virus infections in swine: pathogenesis and diagnosis.A conformational restriction in the influenza A virus neuraminidase binding site by R152 results in a combinational effect of I222T and H274Y on oseltamivir resistance.DBA/2 mouse as an animal model for anti-influenza drug efficacy evaluation.Mutations associated with severity of the pandemic influenza A(H1N1)pdm09 in humans: a systematic review and meta-analysis of epidemiological evidence.Mammalian adaptive mutations of the PA protein of highly pathogenic avian H5N1 influenza virus.A statistical strategy to identify recombinant viral ribonucleoprotein of avian, human, and swine influenza A viruses with elevated polymerase activityUse of fractional factorial design to study the compatibility of viral ribonucleoprotein gene segments of human H7N9 virus and circulating human influenza subtypes.Influenza A viruses with different amino acid residues at PB2-627 display distinct replication properties in vitro and in vivo: revealing the sequence plasticity of PB2-627 positionCrucial role of PA in virus life cycle and host adaptation of influenza A virus.The RNA-dependent RNA polymerase of the influenza A virus.Caspase-1 deficient mice are more susceptible to influenza A virus infection with PA variation.Genetic and codon usage bias analyses of polymerase genes of equine influenza virus and its relation to evolution.The S128N mutation combined with an additional potential N-linked glycosylation site at residue 133 in hemagglutinin affects the antigenicity of the human H7N9 virus.Computational analysis of the effect of polymerase acidic (PA) gene mutation F35L in the 2009 pandemic influenza A (H1N1) virus on binding aspects of mononucleotides in the endonuclease domain.A Single Amino Acid at the Polymerase Acidic Protein Determines the Pathogenicity of Influenza B Viruses.Directed evolution of an influenza reporter virus to restore replication and virulence and enhance non-invasive bioluminescence imaging in mice
P2860
Q27676615-8B2BBA4D-0CBB-41BB-ACF2-897C7BDB6B92Q28388794-3CF76B27-EC17-4BB1-8CCD-412EB2A2DA51Q30356762-65C15D53-4172-4885-8E3E-B81C5D366616Q30357141-D3AB8190-7DDC-403D-AF68-26537227F6C5Q30357193-2C7D64E1-012E-4590-8991-F7987BA954A9Q30357472-2FFB2F3E-3D16-4ED0-B66E-449543342502Q30365296-7C60BDB7-54AC-453C-9F76-F508B885E368Q30371198-CC08D266-328A-439D-99D0-BFC805254078Q30429987-D7D343D7-487B-4184-A2CC-2505EA4D6E35Q34167450-20C4F46F-EAEE-4CE9-AAE0-EAE0844A5A85Q34615966-6F0598B4-1E04-4CE9-9380-8CA3BF827F80Q38234789-5B76CB01-8D42-42F7-AE0A-6029C41C095BQ39093232-BED0F8BA-D252-483A-AD6C-D0C9D2E5B4C5Q39117629-C7123E93-2E05-488A-849D-763D409CAE24Q40075092-4C6F8B01-0B17-4D92-9968-4A806B3ABD91Q42381827-DEBF799E-5DAA-493D-B03D-125C507A8B3CQ47259261-3DE95B92-68F7-426B-9604-6A4575551882Q52324500-8DF97B61-A09B-430A-8933-DFE3F81D887CQ56890034-B1AB861B-6C98-41FE-8EDB-1E86277257FE
P2860
Mutations in polymerase genes enhanced the virulence of 2009 pandemic H1N1 influenza virus in mice
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Mutations in polymerase genes ...... c H1N1 influenza virus in mice
@ast
Mutations in polymerase genes ...... c H1N1 influenza virus in mice
@en
type
label
Mutations in polymerase genes ...... c H1N1 influenza virus in mice
@ast
Mutations in polymerase genes ...... c H1N1 influenza virus in mice
@en
prefLabel
Mutations in polymerase genes ...... c H1N1 influenza virus in mice
@ast
Mutations in polymerase genes ...... c H1N1 influenza virus in mice
@en
P2093
P2860
P1433
P1476
Mutations in polymerase genes ...... c H1N1 influenza virus in mice
@en
P2093
Jianfang Zhou
Rongbao Gao
Wenfei Zhu
Yuelong Shu
Zaijiang Yu
P2860
P304
P356
10.1371/JOURNAL.PONE.0033383
P407
P577
2012-03-15T00:00:00Z