Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice - Wikidata - wikimedia - TriplyDB

Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice

Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice

http://www.wikidata.org/entity/Q30414624

about

Fox tales: regulation of gonadotropin gene expression by forkhead transcription factors Follicle-stimulating hormone synthesis and fertility depend on SMAD4 and FOXL2.β-catenin stabilization in gonadotropes impairs FSH synthesis in male mice in vivo.Follicle-stimulating hormone synthesis and fertility are intact in mice lacking SMAD3 DNA binding activity and SMAD2 in gonadotrope cells.NR5A2 regulates Lhb and Fshb transcription in gonadotrope-like cells in vitro, but is dispensable for gonadotropin synthesis and fertility in vivo.Minireview: Activin Signaling in Gonadotropes: What Does the FOX say… to the SMAD?Pituitary gland development and disease: from stem cell to hormone production Genetic associations with diminished ovarian reserve: a systematic review of the literature The regulation of reproductive neuroendocrine function by insulin and insulin-like growth factor-1 (IGF-1).Roles of binding elements, FOXL2 domains, and interactions with cJUN and SMADs in regulation of FSHβ.Role of Foxl2 in uterine maturation and function.Maximal expression of Foxl2 in pituitary gonadotropes requires ovarian hormones.Loss of Foxm1 Results in Reduced Somatotrope Cell Number during Mouse Embryogenesis.GnRH Pulse Frequency Control of Fshb Gene Expression Is Mediated via ERK1/2 Regulation of ICER The CpG island in the murine foxl2 proximal promoter is differentially methylated in primary and immortalized cells.Sex- and age-specific impact of ERK loss within the pituitary gonadotrope in mice.Gonadotropin regulation by pulsatile GnRH: Signaling and gene expression.SMAD3 Regulates Follicle-stimulating Hormone Synthesis by Pituitary Gonadotrope Cells in Vivo.Molecular Regulation of Follicle-Stimulating Hormone Synthesis, Secretion and Action.GnRH receptor expression and reproductive function depend on JUN in the GnRH receptor-expressing cells.

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Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice

http://www.wikidata.org/entity/Q30414624

description

2013 nî lūn-bûn

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2013 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2013 թվականի հունվարին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice

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Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice

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type

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Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice

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Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice

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prefLabel

Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice

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Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice

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Molecular Endocrinology

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Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice

@en

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Buffy S Ellsworth

http://www.w3.org/2001/XMLSchema#string

Christine Lafleur

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Daniel J Bernard

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Derek Boerboom

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Mathias Treier

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Michael J Calderon

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Stella Tran

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Ulrich Boehm

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Xiang Zhou

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P2860

The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome

Expression of activin subunits and receptors in the developing human ovary: activin A promotes germ cell survival and proliferation before primordial follicle formation

Mutation in the follicle-stimulating hormone receptor gene causes hereditary hypergonadotropic ovarian failure

Primary amenorrhoea and infertility due to a mutation in the beta-subunit of follicle-stimulating hormone

Men homozygous for an inactivating mutation of the follicle-stimulating hormone (FSH) receptor gene present variable suppression of spermatogenesis and fertility

Evolution and expression of FOXL2

FOXL2 and BPES: mutational hotspots, phenotypic variability, and revision of the genotype-phenotype correlation

FoxL2 and Smad3 coordinately regulate follistatin gene transcription

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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407-421

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10.1210/ME.2012-1286

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23340250

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