I223R mutation in influenza A(H1N1)pdm09 neuraminidase confers reduced susceptibility to oseltamivir and zanamivir and enhanced resistance with H275Y - Wikidata - wikimedia - TriplyDB

I223R mutation in influenza A(H1N1)pdm09 neuraminidase confers reduced susceptibility to oseltamivir and zanamivir and enhanced resistance with H275Y

I223R mutation in influenza A(H1N1)pdm09 neuraminidase confers reduced susceptibility to oseltamivir and zanamivir and enhanced resistance with H275Y

http://www.wikidata.org/entity/Q30420810

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Impact of the H275Y and I223V Mutations in the Neuraminidase of the 2009 Pandemic Influenza Virus In Vitro and Evaluating Experimental Reproducibility A Novel I221L Substitution in Neuraminidase Confers High-Level Resistance to Oseltamivir in Influenza B Viruses Genetic Characterization of Circulating 2015 A(H1N1)pdm09 Influenza Viruses from Eastern India In silico study on multidrug resistance conferred by I223R/H275Y double mutant neuraminidase.A conformational restriction in the influenza A virus neuraminidase binding site by R152 results in a combinational effect of I222T and H274Y on oseltamivir resistance.Profiling and characterization of influenza virus N1 strains potentially resistant to multiple neuraminidase inhibitors.Pseudovirus-based neuraminidase inhibition assays reveal potential H5N1 drug-resistant mutations.Temperature-Sensitive Mutants in the Influenza A Virus RNA Polymerase: Alterations in the PA Linker Reduce Nuclear Targeting of the PB1-PA Dimer and Result in Viral Attenuation Virological characterization of influenza H1N1pdm09 in Vietnam, 2010-2013.Immunomodulatory Activity and Protective Effects of Polysaccharide from Eupatorium adenophorum Leaf Extract on Highly Pathogenic H5N1 Influenza Infection Microsecond Molecular Dynamics Simulations of Influenza Neuraminidase Suggest a Mechanism for the Increased Virulence of Stalk-Deletion Mutants.Development of oseltamivir and zanamivir resistance in influenza A(H1N1)pdm09 virus, Denmark, 2014.A Review of Clinical Influenza A and B Infections With Reduced Susceptibility to Both Oseltamivir and Zanamivir.Susceptibility of influenza A(H1N1)/pdm2009, seasonal A(H3N2) and B viruses to Oseltamivir in Guangdong, China between 2009 and 2014.Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains.Characterization of the neuraminidase genes from human influenza A viruses circulating in Iran from 2010 to 2015.Discovery of Potent Neuraminidase Inhibitors Using a Combination of Pharmacophore-Based Virtual Screening and Molecular Simulation Approach.A comparison of RSV and influenza in vitro kinetic parameters reveals differences in infecting time.

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I223R mutation in influenza A(H1N1)pdm09 neuraminidase confers reduced susceptibility to oseltamivir and zanamivir and enhanced resistance with H275Y

http://www.wikidata.org/entity/Q30420810

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2012 nî lūn-bûn

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2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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P2860

New low-viscosity overlay medium for viral plaque assays

Oseltamivir resistance during treatment of influenza A (H5N1) infection

Natural variation can significantly alter the sensitivity of influenza A (H5N1) viruses to oseltamivir.

Zanamivir-resistant influenza viruses with a novel neuraminidase mutation

Oseltamivir-resistant 2009 pandemic influenza A (H1N1) virus infection in two summer campers receiving prophylaxis--North Carolina, 2009.

Oseltamivir-resistant influenza A pandemic (H1N1) 2009 virus, Hong Kong, China.

Detection of molecular markers of drug resistance in 2009 pandemic influenza A (H1N1) viruses by pyrosequencing.

Oseltamivir-resistant 2009-2010 pandemic influenza A (H1N1) in an immunocompromised patient.

Oseltamivir-induced resistant pandemic A/H1N1 influenza virus in a child with cystic fibrosis and Pseudomonas aeruginosa infection.

The emergence of oseltamivir-resistant pandemic influenza A (H1N1) 2009 virus amongst hospitalised immunocompromised patients in Scotland, November-December, 2009.

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