Binding site detection and druggability prediction of protein targets for structure-based drug design.
about
HotSpot Wizard 2.0: automated design of site-specific mutations and smart libraries in protein engineering.Comparative analyses of lipoprotein lipase, hepatic lipase, and endothelial lipase, and their binding properties with known inhibitors.iDrug: a web-accessible and interactive drug discovery and design platform.SPILLO-PBSS: detecting hidden binding sites within protein 3D-structures through a flexible structure-based approach.Binding cavities and druggability of intrinsically disordered proteins.Computational Advances for the Development of Allosteric Modulators and Bitopic Ligands in G Protein-Coupled ReceptorsStructure-based Inhibitor Design for the Intrinsically Disordered Protein c-Myc.Targeting L-type amino acid transporter 1 for anticancer therapy: clinical impact from diagnostics to therapeutics.Rational design, synthesis, and biological evaluation of Pan-Raf inhibitors to overcome resistance.PharmMapper 2017 update: a web server for potential drug target identification with a comprehensive target pharmacophore database.Protein-protein interaction inhibitors: advances in anticancer drug design.Can We Rely on Computational Predictions To Correctly Identify Ligand Binding Sites on Novel Protein Drug Targets? Assessment of Binding Site Prediction Methods and a Protocol for Validation of Predicted Binding Sites.Are label-free investigations the best approach to drug discovery?Computational identification of a new binding site in influenza virus hemagglutinin for membrane fusion inhibitors.Rational Design of Selective Allosteric Inhibitors of PHGDH and Serine Synthesis with Anti-tumor Activity.Discovery of Non-ATP-Competitive Inhibitors of Polo-like Kinase 1.Allosteric sites can be identified based on the residue-residue interaction energy difference.Reverse Screening Methods to Search for the Protein Targets of Chemopreventive Compounds.CavityPlus: a web server for protein cavity detection with pharmacophore modelling, allosteric site identification and covalent ligand binding ability prediction.Activation of Glutathione Peroxidase 4 as a Novel Anti-inflammatory Strategy
P2860
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P2860
Binding site detection and druggability prediction of protein targets for structure-based drug design.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Binding site detection and dru ...... r structure-based drug design.
@ast
Binding site detection and dru ...... r structure-based drug design.
@en
type
label
Binding site detection and dru ...... r structure-based drug design.
@ast
Binding site detection and dru ...... r structure-based drug design.
@en
prefLabel
Binding site detection and dru ...... r structure-based drug design.
@ast
Binding site detection and dru ...... r structure-based drug design.
@en
P1476
Binding site detection and dru ...... r structure-based drug design.
@en
P2093
Jianfeng Pei
P304
P356
10.2174/1381612811319120019
P50
P577
2013-01-01T00:00:00Z