Activation of the insulin-like growth factor-1 receptor induces resistance to epidermal growth factor receptor antagonism in head and neck squamous carcinoma cells.
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Activation of the insulin-like growth factor-1 receptor alters p27 regulation by the epidermal growth factor receptor in oral squamous carcinoma cellsNicotine enhances proliferation, migration, and radioresistance of human malignant glioma cells through EGFR activation.Nanoimmunoassay to Detect Responses in Head and Neck Cancer: Feasibility in a Mouse Model.Synergistic apoptosis in head and neck squamous cell carcinoma cells by co-inhibition of insulin-like growth factor-1 receptor signaling and compensatory signaling pathways.A New Bliss Independence Model to Analyze Drug Combination Data.Dual blockade of epidermal growth factor receptor and insulin-like growth factor receptor-1 signaling in metastatic pancreatic cancer: phase Ib and randomized phase II trial of gemcitabine, erlotinib, and cixutumumab versus gemcitabine plus erlotiniReverse-phase protein array profiling of oropharyngeal cancer and significance of PIK3CA mutations in HPV-associated head and neck cancer.Combination of anti-HER3 antibody MM-121/SAR256212 and cetuximab inhibits tumor growth in preclinical models of head and neck squamous cell carcinomaInsulin-like growth factor 1 receptor (IGF1R) expression and survival in operable squamous-cell laryngeal cancer.Redundant kinase activation and resistance of EGFR-tyrosine kinase inhibitors.Insulin-like growth factor (IGF) signaling in tumorigenesis and the development of cancer drug resistance.Deguelin induces apoptosis by targeting both EGFR-Akt and IGF1R-Akt pathways in head and neck squamous cell cancer cell lines.Acquired resistance to drugs targeting receptor tyrosine kinasesTGFβ receptor 1: an immune susceptibility gene in HPV-associated cancer.BMS-754807 is cytotoxic to non-small cell lung cancer cells and enhances the effects of platinum chemotherapeutics in the human lung cancer cell line A549.Antiepidermal growth factor receptor therapy in squamous cell carcinoma of the head and neck.Insulin growth factor 1 like receptor (IGF-1R).MicroRNA-7 enhances cytotoxicity induced by gefitinib in non-small cell lung cancer via inhibiting the EGFR and IGF1R signalling pathways.Molecular imaging of insulin-like growth factor 1 receptor in cancer.miR-223 enhances the sensitivity of non-small cell lung cancer cells to erlotinib by targeting the insulin-like growth factor-1 receptor.Morphoproteomics and biomedical analytics confirm the mTORC2/Akt pathway as a resistance signature and activated ERK and STAT3 as concomitant prosurvival/antiapoptotic pathways in metastatic renal cell carcinoma (RCC) progressing on rapalogs: pathogHypoxia increases gefitinib-resistant lung cancer stem cells through the activation of insulin-like growth factor 1 receptor.α6 integrin transactivates insulin-like growth factor receptor-1 (IGF-1R) to regulate caspase-3-mediated lens epithelial cell differentiation initiation.Type I insulin-like growth factor receptor signaling in hematological malignancies.Adaptive protein and phosphoprotein networks which promote therapeutic sensitivity or acquired resistance.Activation of an AKT/FOXM1/STMN1 pathway drives resistance to tyrosine kinase inhibitors in lung cancer.Targeting pathways mediating resistance to anti-EGFR therapy in squamous cell carcinoma of the head and neck.Inhibition of EGFR or IGF-1R signaling enhances radiation response in head and neck cancer models but concurrent inhibition has no added benefit.3q26-29 Amplification in head and neck squamous cell carcinoma: a review of established and prospective oncogenes.Antitumor mechanisms of targeting the PDK1 pathway in head and neck cancer.Receptor tyrosine kinase profiles and human papillomavirus status in oropharyngeal squamous cell carcinoma.A phase II trial of dacomitinib, an oral pan-human EGF receptor (HER) inhibitor, as first-line treatment in recurrent and/or metastatic squamous-cell carcinoma of the head and neck.Locally advanced head and neck squamous cell cancer: treatment choice based on risk factors and optimizing drug prescription.Acquired Resistance to Drugs Targeting Tyrosine Kinases.
P2860
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P2860
Activation of the insulin-like growth factor-1 receptor induces resistance to epidermal growth factor receptor antagonism in head and neck squamous carcinoma cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Activation of the insulin-like ...... neck squamous carcinoma cells.
@ast
Activation of the insulin-like ...... neck squamous carcinoma cells.
@en
type
label
Activation of the insulin-like ...... neck squamous carcinoma cells.
@ast
Activation of the insulin-like ...... neck squamous carcinoma cells.
@en
prefLabel
Activation of the insulin-like ...... neck squamous carcinoma cells.
@ast
Activation of the insulin-like ...... neck squamous carcinoma cells.
@en
P2093
P2860
P1476
Activation of the insulin-like ...... neck squamous carcinoma cells.
@en
P2093
Amir Allak
Andrew D Beckler
Christopher Y Thomas
Linnea E Taniguchi
Mark J Jameson
Matthew A Hubbard
Nora G Lee
William C Thomsen
P2860
P304
P356
10.1158/1535-7163.MCT-11-0294
P577
2011-08-30T00:00:00Z