about
Computational design of a PDZ domain peptide inhibitor that rescues CFTR activityImproved prediction of protein side-chain conformations with SCWRL4Structure of a protein G helix variant suggests the importance of helix propensity and helix dipole interactions in protein designSide-chain repacking calculations for predicting structures and stabilities of heterodimeric coiled coilsCrystal structures and increased stabilization of the protein G variants with switched folding pathways NuG1 and NuG2Computational design and experimental study of tighter binding peptides to an inactivated mutant of HIV-1 proteaseHIV-1 Protease Inhibitors from Inverse Design in the Substrate Envelope Exhibit Subnanomolar Binding to Drug-Resistant VariantsCysteine-free rop: A four-helix bundle core mutant has wild-type stability and structure but dramatically different unfolding kineticsIterative approach to computational enzyme designDe novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificityProtein design: Past, present, and futureRational protein design: developing next-generation biological therapeutics and nanobiotechnological toolsDesign, synthesis, and characterization of a novel hemoproteinEfficient calculation of molecular configurational entropies using an information theoretic approximationEfficient Computation of Small-Molecule Configurational Binding Entropy and Free Energy Changes by Ensemble EnumerationMapping the Geometric Evolution of Protein Folding MotorROSETTA3: an object-oriented software suite for the simulation and design of macromoleculesA simple model of backbone flexibility improves modeling of side-chain conformational variabilityRational design of intercellular adhesion molecule-1 (ICAM-1) variants for antagonizing integrin lymphocyte function-associated antigen-1-dependent adhesionA graph-theory algorithm for rapid protein side-chain predictionComputational protein design: the Proteus software and selected applications.Computational protein design: validation and possible relevance as a tool for homology searching and fold recognitionComputational design of receptor and sensor proteins with novel functions.One- and two-body decomposable Poisson-Boltzmann methods for protein design calculations.Computational approaches for rational design of proteins with novel functionalitiesRotamer optimization for protein design through MAP estimation and problem-size reduction.PROTDES: CHARMM toolbox for computational protein design.In silico saturation mutagenesis and docking screening for the analysis of protein-ligand interaction: the Endothelial Protein C Receptor case study.Achievements and Challenges in Computational Protein Design.RASP: rapid modeling of protein side chain conformations.De novo design of the hydrophobic core of ubiquitin.Computational method to reduce the search space for directed protein evolution.Knowledge-based potential defined for a rotamer library to design protein sequences.Statistical theory for protein ensembles with designed energy landscapes.TransCent: computational enzyme design by transferring active sites and considering constraints relevant for catalysis.AutoMatch: target-binding protein design and enzyme design by automatic pinpointing potential active sites in available protein scaffolds.Protein design is NP-hard.Strategies to control the binding mode of de novo designed protein interactions.Combining computational and experimental screening for rapid optimization of protein propertiesEngineered antibody Fc variants with enhanced effector function.
P2860
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P2860
description
1996 nî lūn-bûn
@nan
1996 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Protein design automation.
@ast
Protein design automation.
@en
type
label
Protein design automation.
@ast
Protein design automation.
@en
prefLabel
Protein design automation.
@ast
Protein design automation.
@en
P2860
P356
P1433
P1476
Protein design automation.
@en
P2093
P2860
P304
P356
10.1002/PRO.5560050511
P577
1996-05-01T00:00:00Z