Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front-back polarity in migrating cells
about
The dynamics of spatio-temporal Rho GTPase signaling: formation of signaling patternsCell polarity signaling in the plasticity of cancer cell invasivenessNon-muscle myosin II in disease: mechanisms and therapeutic opportunitiesThe on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migrationNonmuscle myosin-2: mix and matchROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity.Non-muscle myosin IIB is critical for nuclear translocation during 3D invasion.The tandem PH domain-containing protein 2 (TAPP2) regulates chemokine-induced cytoskeletal reorganization and malignant B cell migrationMst1 directs Myosin IIa partitioning of low and higher affinity integrins during T cell migrationSubstrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectinThe integrin-ligand interaction regulates adhesion and migration through a molecular clutch.Actomyosin stress fiber mechanosensing in 2D and 3DA biomechanical perspective on stress fiber structure and functionEndogenous species of mammalian nonmuscle myosin IIA and IIB include activated monomers and heteropolymers.Microtubule guidance tested through controlled cell geometry.Chondroitin Sulfate Impairs Neural Stem Cell Migration Through ROCK Activation.Signaling networks that regulate cell migrationA regulatory motif in nonmuscle myosin II-B regulates its role in migratory front-back polarityMatrix microarchitecture and myosin II determine adhesion in 3D matrices.Distinct signaling mechanisms regulate migration in unconfined versus confined spacesFluorescence fluctuation approaches to the study of adhesion and signalingAdhesion dynamics at a glance.Myosin light chain kinase regulates cell polarization independently of membrane tension or Rho kinase.A resilient formin-derived cortical actin meshwork in the rear drives actomyosin-based motility in 2D confinementComputational model of mesenchymal migration in 3D under chemotaxis.LIMCH1 regulates nonmuscle myosin-II activity and suppresses cell migration.Polarized Distribution of Active Myosin II Regulates Directional Migration of Cultured Olfactory Ensheathing Cells.Mechanical checkpoint for persistent cell polarization in adhesion-naive fibroblastsStochastic models of cell protrusion arising from spatiotemporal signaling and adhesion dynamicsSimultaneous and independent tuning of RhoA and Rac1 activity with orthogonally inducible promoters.Rac1-dependent phosphorylation and focal adhesion recruitment of myosin IIA regulates migration and mechanosensing.Myosin II isoform co-assembly and differential regulation in mammalian systemsDifferential Contributions of Nonmuscle Myosin II Isoforms and Functional Domains to Stress Fiber Mechanics.The Rac activator Tiam1 is required for polarized protrusional outgrowth of primary astrocytes by affecting the organization of the microtubule network.Fibroblast Migration in 3D is Controlled by Haptotaxis in a Non-muscle Myosin II-Dependent Manner.Oridonin suppress cell migration via regulation of nonmuscle myosin IIA.A Perspective on the Role of Myosins as MechanosensorsArf guanine nucleotide-exchange factors BIG1 and BIG2 regulate nonmuscle myosin IIA activity by anchoring myosin phosphatase complex.Substrates with engineered step changes in rigidity induce traction force polarity and durotaxis.Rac1/RhoA antagonism defines cell-to-cell heterogeneity during epidermal morphogenesis in nematodes.
P2860
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P2860
Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front-back polarity in migrating cells
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Myosin IIA/IIB restrict adhesi ...... ck polarity in migrating cells
@ast
Myosin IIA/IIB restrict adhesi ...... ck polarity in migrating cells
@en
type
label
Myosin IIA/IIB restrict adhesi ...... ck polarity in migrating cells
@ast
Myosin IIA/IIB restrict adhesi ...... ck polarity in migrating cells
@en
prefLabel
Myosin IIA/IIB restrict adhesi ...... ck polarity in migrating cells
@ast
Myosin IIA/IIB restrict adhesi ...... ck polarity in migrating cells
@en
P2860
P50
P356
P1476
Myosin IIA/IIB restrict adhesi ...... ck polarity in migrating cells
@en
P2093
Alexia I Bachir
Leanna A Whitmore
P2860
P304
P356
10.1083/JCB.201012159
P407
P577
2011-04-11T00:00:00Z