Site-specific inhibitory mechanism for amyloid β42 aggregation by catechol-type flavonoids targeting the Lys residues.
about
Possible protective action of neurotrophic factors and natural compounds against common neurodegenerative diseasesA Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms.Structural Mechanism of the Interaction of Alzheimer Disease Aβ Fibrils with the Non-steroidal Anti-inflammatory Drug (NSAID) Sulindac SulfideAmyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies.7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease.Identification of aggregation inhibitors of the human antibody light chain repertoire by phage display.Benzbromarone, Quercetin, and Folic Acid Inhibit Amylin AggregationTaxifolin inhibits amyloid-β oligomer formation and fully restores vascular integrity and memory in cerebral amyloid angiopathy.Conformation-specific antibodies to target amyloid β oligomers and their application to immunotherapy for Alzheimer's disease.Quercetin and related polyphenols: new insights and implications for their bioactivity and bioavailability.Anti-amyloid Aggregation Activity of Natural Compounds: Implications for Alzheimer's Drug Discovery.Perspectives on Inhibiting β-Amyloid Aggregation through Structure-Based Drug Design.Role of norepinephrine in Aβ-related neurotoxicity: dual interactions with Tyr10 and SNK(26-28) of Aβ.Natural product-based amyloid inhibitors.Aβ-Induced Insulin Resistance and the Effects of Insulin on the Cholesterol Synthesis Pathway and Aβ Secretion in Neural Cells.Anthocyanin suppresses the toxicity of Aβ deposits through diversion of molecular forms in in vitro and in vivo models of Alzheimer's disease.Effect of the Tottori familial disease mutation (D7N) on the monomers and dimers of Aβ40 and Aβ42.Inhibition of HEWL fibril formation by taxifolin: Mechanism of action.Polyamine Conjugation as a Promising Strategy To Target Amyloid Aggregation in the Framework of Alzheimer's Disease.Bioactive polyphenol interactions with β amyloid: a comparison of binding modelling, effects on fibril and aggregate formation and neuroprotective capacity.Amyloid-beta (Aβ₁₋₄₂)-induced paralysis in Caenorhabditis elegans is inhibited by the polyphenol quercetin through activation of protein degradation pathways.Targeting Amyloid Aggregation: An Overview of Strategies and MechanismsEffects of hydroxyl group variations on a flavonoid backbone toward modulation of metal-free and metal-induced amyloid-β aggregation
P2860
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P2860
Site-specific inhibitory mechanism for amyloid β42 aggregation by catechol-type flavonoids targeting the Lys residues.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Site-specific inhibitory mecha ...... ds targeting the Lys residues.
@ast
Site-specific inhibitory mecha ...... ds targeting the Lys residues.
@en
type
label
Site-specific inhibitory mecha ...... ds targeting the Lys residues.
@ast
Site-specific inhibitory mecha ...... ds targeting the Lys residues.
@en
prefLabel
Site-specific inhibitory mecha ...... ds targeting the Lys residues.
@ast
Site-specific inhibitory mecha ...... ds targeting the Lys residues.
@en
P2093
P2860
P356
P1476
Site-specific inhibitory mecha ...... ds targeting the Lys residues.
@en
P2093
Kazuma Murakami
Ken-ichi Akagi
Kiyonori Takegoshi
Mayumi Uno
Mizuho Sato
Sumie Katayama
Yu Nakagawa
Yuichi Masuda
P2860
P304
23212-23224
P356
10.1074/JBC.M113.464222
P407
P577
2013-06-21T00:00:00Z