Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration.
about
Rho, ROCK and actomyosin contractility in metastasis as drug targetsRho GTPase signalling in cell migrationPhysical biology in cancer. 4. Physical cues guide tumor cell adhesion and migrationHuman neutrophil cytoskeletal dynamics and contractility actively contribute to trans-endothelial migrationA translocated effector required for Bartonella dissemination from derma to blood safeguards migratory host cells from damage by co-translocated effectorsThe RhoA-ROCK pathway in the regulation of T and B cell responsesGene targeting RhoA reveals its essential role in coordinating mitochondrial function and thymocyte developmentCdc42 promotes transendothelial migration of cancer cells through β1 integrin.HIV-1 Nef interferes with T-lymphocyte circulation through confined environments in vivo.A role for LFA-1 in delaying T-lymphocyte egress from lymph nodes.Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering Rho GTPase signaling that is reversible with lenalidomide.GEF-H1 functions in apical constriction and cell intercalations and is essential for vertebrate neural tube closure.Autophagy and SQSTM1 on the RHOA(d) again: emerging roles of autophagy in the degradation of signaling proteins.Cadherin 6 promotes neural crest cell detachment via F-actin regulation and influences active Rho distribution during epithelial-to-mesenchymal transition.The curious origins of angioimmunoblastic T-cell lymphomaHeparanase-induced GEF-H1 signaling regulates the cytoskeletal dynamics of brain metastatic breast cancer cells.A multi-functional imaging approach to high-content protein interaction screeningTargeting Rho-GTPases in immune cell migration and inflammation.Hax1 regulates neutrophil adhesion and motility through RhoA.RhoA and RhoC have distinct roles in migration and invasion by acting through different targets.RhoA Kinase (Rock) and p90 Ribosomal S6 Kinase (p90Rsk) phosphorylation of the sodium hydrogen exchanger (NHE1) is required for lysophosphatidic acid-induced transport, cytoskeletal organization and migration.Analysis of Rho GTPase expression in T-ALL identifies RhoU as a target for Notch involved in T-ALL cell migrationMicrotubules regulate GEF-H1 in response to extracellular matrix stiffness.ROCK activity and the Gβγ complex mediate chemotactic migration of mouse bone marrow-derived stromal cellsRhoA orchestrates glycolysis for TH2 cell differentiation and allergic airway inflammation.Autotaxin through lysophosphatidic acid stimulates polarization, motility, and transendothelial migration of naive T cellsARHGEF15 overexpression worsens the prognosis in patients with pancreatic ductal adenocarcinoma through enhancing the motility and proliferative activity of the cancer cells.The focal adhesion kinase inhibitor PF-562,271 impairs primary CD4+ T cell activation.PDZ-RhoGEF is essential for CXCR4-driven breast tumor cell motility through spatial regulation of RhoA.GEF-H1 is necessary for neutrophil shear stress-induced migration during inflammation.The role of RhoA/Rho kinase pathway in endothelial dysfunctionHow Förster resonance energy transfer imaging improves the understanding of protein interaction networks in cancer biology.The challenges of integrating molecular imaging into the optimization of cancer therapy.Advanced intravital subcellular imaging reveals vital three-dimensional signalling events driving cancer cell behaviour and drug responses in live tissue.Roles of Rho GTPases in leucocyte and leukaemia cell transendothelial migrationImaging early signaling events in T lymphocytes with fluorescent biosensors.Follicular helper T-cells: expanding roles in T-cell lymphoma and targets for treatment.Rho GTPase isoforms in cell motility: Don't fret, we have FRET.Leading from the Back: The Role of the Uropod in Neutrophil Polarization and Migration.Apoptin interacts with and regulates the activity of protein kinase C beta in cancer cells.
P2860
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P2860
Coordinated RhoA signaling at the leading edge and uropod is required for T cell transendothelial migration.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Coordinated RhoA signaling at ...... ll transendothelial migration.
@ast
Coordinated RhoA signaling at ...... ll transendothelial migration.
@en
type
label
Coordinated RhoA signaling at ...... ll transendothelial migration.
@ast
Coordinated RhoA signaling at ...... ll transendothelial migration.
@en
prefLabel
Coordinated RhoA signaling at ...... ll transendothelial migration.
@ast
Coordinated RhoA signaling at ...... ll transendothelial migration.
@en
P2860
P50
P356
P1476
Coordinated RhoA signaling at ...... ll transendothelial migration.
@en
P2093
Sarah J Heasman
P2860
P304
P356
10.1083/JCB.201002067
P407
P577
2010-08-01T00:00:00Z