Insulin-stimulated interaction with 14-3-3 promotes cytoplasmic localization of lipin-1 in adipocytes.
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Lipins, lipinopathies, and the modulation of cellular lipid storage and signalingHomo sapiens dullard protein phosphatase shows a preference for the insulin-dependent phosphorylation site of lipin1Lipin 1 represses NFATc4 transcriptional activity in adipocytes to inhibit secretion of inflammatory factorsLipin1 Regulates Skeletal Muscle Differentiation through Extracellular Signal-regulated Kinase (ERK) Activation and Cyclin D Complex-regulated Cell Cycle Withdrawal.Lipin 2 binds phosphatidic acid by the electrostatic hydrogen bond switch mechanism independent of phosphorylation.Conserved residues in the N terminus of lipin-1 are required for binding to protein phosphatase-1c, nuclear translocation, and phosphatidate phosphatase activity.Phosphorylation of lipin 1 and charge on the phosphatidic acid head group control its phosphatidic acid phosphatase activity and membrane association.mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.Dual function lipin proteins and glycerolipid metabolismLipin proteins form homo- and hetero-oligomersA phosphatidic acid binding/nuclear localization motif determines lipin1 function in lipid metabolism and adipogenesisCharacterization of the human LPIN1-encoded phosphatidate phosphatase isoforms.Phosphorylation of phosphatidate phosphatase regulates its membrane association and physiological functions in Saccharomyces cerevisiae: identification of SER(602), THR(723), AND SER(744) as the sites phosphorylated by CDC28 (CDK1)-encoded cyclin-deThe peripheral binding of 14-3-3γ to membranes involves isoform-specific histidine residues.Identification of a novel lipin homologue from the parasitic protozoan Trypanosoma brucei.Lipin-1γ isoform is a novel lipid droplet-associated protein highly expressed in the brainMammalian triacylglycerol metabolism: synthesis, lipolysis, and signalingGlucose-6-phosphate isomerase deficiency results in mTOR activation, failed translocation of lipin 1α to the nucleus and hypersensitivity to glucose: Implications for the inherited glycolytic diseaseOntogenetic Expression of Lpin2 and Lpin3 Genes and Their Associations with Traits in Two Breeds of Chinese Fat-tailed SheepSignal Transduction Mechanisms of Alcoholic Fatty Liver Disease: Emerging Role of Lipin-1.Lipin-1 and lipin-3 together determine adiposity in vivo.The role of lipin-1 in the pathogenesis of alcoholic fatty liver.14-3-3γ affects mTOR pathway and regulates lactogenesis in dairy cow mammary epithelial cells.Lipin proteins and glycerolipid metabolism: Roles at the ER membrane and beyond.Differential expression and accumulation of 14-3-3 paralogs in 3T3-L1 preadipocytes and differentiated cells.Molecular characterisation of two homoeologous elicitor-responsive lipin genes in cotton.PAS kinase drives lipogenesis through SREBP-1 maturation.Phosphatidic acid phosphohydrolase 1 and 2 regulate phospholipid synthesis at the endoplasmic reticulum in Arabidopsis.The Phosphatidic Acid-Binding, Polybasic Domain is Responsible for the Differences in the Phosphoregulation of Lipins 1 and 3.Endocrine and physiological regulation of neutral fat storage in Drosophila.The binding of 14-3-3γ to membranes studied by intrinsic fluorescence spectroscopy.Exploring Seipin: From Biochemistry to Bioinformatics Predictions
P2860
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P2860
Insulin-stimulated interaction with 14-3-3 promotes cytoplasmic localization of lipin-1 in adipocytes.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Insulin-stimulated interaction ...... tion of lipin-1 in adipocytes.
@ast
Insulin-stimulated interaction ...... tion of lipin-1 in adipocytes.
@en
type
label
Insulin-stimulated interaction ...... tion of lipin-1 in adipocytes.
@ast
Insulin-stimulated interaction ...... tion of lipin-1 in adipocytes.
@en
prefLabel
Insulin-stimulated interaction ...... tion of lipin-1 in adipocytes.
@ast
Insulin-stimulated interaction ...... tion of lipin-1 in adipocytes.
@en
P2093
P2860
P356
P1476
Insulin-stimulated interaction ...... tion of lipin-1 in adipocytes.
@en
P2093
Miklós Péterfy
Naoya Fujita
Thurl E Harris
P2860
P304
P356
10.1074/JBC.M109.072488
P407
P50
P577
2009-12-02T00:00:00Z