Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD.
about
The Physiology of Fear: Reconceptualizing the Role of the Central Amygdala in Fear LearningFrom the neurobiology of extinction to improved clinical treatments.Prevention of Trauma and Stressor-Related Disorders: A ReviewNociceptin and the nociceptin receptor in learning and memoryThe Genetics of Stress-Related Disorders: PTSD, Depression, and Anxiety DisordersGenetic influences on the neural and physiological bases of acute threat: A research domain criteria (RDoC) perspective.Asparagine synthetase deficiency detected by whole exome sequencing causes congenital microcephaly, epileptic encephalopathy and psychomotor delay.An Overview of Translationally Informed Treatments for Posttraumatic Stress Disorder: Animal Models of Pavlovian Fear Conditioning to Human Clinical TrialsNociceptin/orphanin FQ peptide receptor antagonist JTC-801 reverses pain and anxiety symptoms in a rat model of post-traumatic stress disorderDirect targeting of peptidergic amygdalar neurons by noradrenergic afferents: linking stress-integrative circuitryVoxel-based morphometry predicts shifts in dendritic spine density and morphology with auditory fear conditioningA role for Tac2, NkB, and Nk3 receptor in normal and dysregulated fear memory consolidation.Expression profiling associates blood and brain glucocorticoid receptor signaling with trauma-related individual differences in both sexesPrinciples for developing animal models of military PTSD.Effects of sex and deletion of neuropeptide Y2 receptors from GABAergic neurons on affective and alcohol drinking behaviors in miceThe role of orphanin FQ/nociceptin in neuroplasticity: relationship to stress, anxiety and neuroinflammation.Heterogeneity in signaled active avoidance learning: substantive and methodological relevance of diversity in instrumental defensive responses to threat cuesDexamethasone Treatment Leads to Enhanced Fear Extinction and Dynamic Fkbp5 Regulation in AmygdalaNeuroimaging genetic approaches to Posttraumatic Stress Disorder.Effects of the NOP agonist SCH221510 on producing and attenuating reinforcing effects as measured by drug self-administration in rats.Amygdala-Dependent Molecular Mechanisms of the Tac2 Pathway in Fear Learning.Decreased expression of nociceptin/orphanin FQ in the dorsal anterior cingulate cortex of suicidesNociceptin receptor activation does not alter acquisition, expression, extinction and reinstatement of conditioned cocaine preference in miceIndividual differences in frontolimbic circuitry and anxiety emerge with adolescent changes in endocannabinoid signaling across species.A genome-wide identified risk variant for PTSD is a methylation quantitative trait locus and confers decreased cortical activation to fearful facesThe nociceptin/orphanin FQ receptor agonist SR-8993 as a candidate therapeutic for alcohol use disorders: validation in rat models."Soldier's Heart": A Genetic Basis for Elevated Cardiovascular Disease Risk Associated with Post-traumatic Stress Disorder.Nociceptin/orphanin FQ decreases glutamate transmission and blocks ethanol-induced effects in the central amygdala of naive and ethanol-dependent rats.The potential of epigenetics in stress-enhanced fear learning models of PTSD.Genetic approaches for the study of PTSD: Advances and challenges.Biological underpinnings of trauma and post-traumatic stress disorder: focusing on genetics and epigenetics.On the Road to Translation for PTSD Treatment: Theoretical and Practical Considerations of the Use of Human Models of Conditioned Fear for Drug Development.Animal Models of PTSD: A Critical Review.Genome-wide gene-based analysis suggests an association between Neuroligin 1 (NLGN1) and post-traumatic stress disorder.Localization of the delta opioid receptor and corticotropin-releasing factor in the amygdalar complex: role in anxiety.Preventing the pain of PTSD.Glasgow Coma Scores, early opioids, and posttraumatic stress disorder among combat amputees.Expression of the PPM1F Gene Is Regulated by Stress and Associated With Anxiety and Depression.Identification of a novel gene regulating amygdala-mediated fear extinction.Serine Racemase and D-serine in the Amygdala Are Dynamically Involved in Fear Learning.
P2860
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P2860
Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD.
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD.
@ast
Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD.
@en
type
label
Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD.
@ast
Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD.
@en
prefLabel
Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD.
@ast
Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD.
@en
P2093
P2860
P1476
Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD.
@en
P2093
Bekh Bradley
Claes Wahlestedt
Elisabeth B Binder
Hasib Salah-Uddin
Jennifer S Stevens
Lynn Almli
Michael Cameron
Raül Andero
Shaun P Brothers
Tanja Jovanovic
P2860
P304
P356
10.1126/SCITRANSLMED.3005656
P407
P577
2013-06-01T00:00:00Z