Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice
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Endothelial Barrier and Its Abnormalities in Cardiovascular DiseaseMacrophages in the pathogenesis of atherosclerosisFlow-dependent cellular mechanotransduction in atherosclerosis.Human haemodynamic frequency harmonics regulate the inflammatory phenotype of vascular endothelial cells.Hemodynamic activation of beta-catenin and T-cell-specific transcription factor signaling in vascular endothelium regulates fibronectin expression.Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammationLocalized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathwayCoronary artery remodeling in a model of left ventricular pressure overload is influenced by platelets and inflammatory cells.Zinc oxide nanoparticle-induced atherosclerotic alterations in vitro and in vivo.Circulating endothelial microparticles in diabetes mellitusPECAM-1: conflicts of interest in inflammation.CD31+ cells represent highly angiogenic and vasculogenic cells in bone marrow: novel role of nonendothelial CD31+ cells in neovascularization and their therapeutic effects on ischemic vascular disease.Intima modifier locus 2 controls endothelial cell activation and vascular permeability.Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectivesTie1 attenuation reduces murine atherosclerosis in a dose-dependent and shear stress-specific mannerRelative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity.PKCzeta decreases eNOS protein stability via inhibitory phosphorylation of ERK5.Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex.Inhibition of c-Jun N-terminal kinase attenuates low shear stress-induced atherogenesis in apolipoprotein E-deficient miceRole of PECAM-1 in arteriogenesis and specification of preexisting collateralsMechanosignaling in the vasculature: emerging concepts in sensing, transduction and physiological responsesP2Y₂ and Gq/G₁₁ control blood pressure by mediating endothelial mechanotransduction.Monocyte trafficking across the vessel wallPECAM1 regulates flow-mediated Gab1 tyrosine phosphorylation and signaling.The anti-inflammatory actions of platelet endothelial cell adhesion molecule-1 do not involve regulation of endothelial cell NF-kappa B.Shear stress modulates VCAM-1 expression in response to TNF-α and dietary lipids via interferon regulatory factor-1 in cultured endotheliumPECAM-1 is necessary for flow-induced vascular remodelingHaemodynamics Regulate Fibronectin Assembly via PECAM.Lessons from the endothelial junctional mechanosensory complex.Role of Tie1 in shear stress and atherosclerosis.Molecular biology of atherosclerosis.PECAM-1: regulator of endothelial junctional integrity.Shear stress and atherosclerosisThe influence of a spatiotemporal 3D environment on endothelial cell differentiation of human induced pluripotent stem cellsEffects of shear stress on endothelial cells: go with the flow.Endothelial Mechanosignaling: Does One Sensor Fit All?Do the Apoe-/- and Ldlr-/- Mice Yield the Same Insight on Atherogenesis?A Revised Hemodynamic Theory of Age-Related Macular Degeneration.Biomechanical factors in atherosclerosis: mechanisms and clinical implications.In Development-A New Paradigm for Understanding Vascular Disease.
P2860
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P2860
Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Endothelial cell PECAM-1 promo ...... ed flow in ApoE-deficient mice
@ast
Endothelial cell PECAM-1 promo ...... ed flow in ApoE-deficient mice
@en
type
label
Endothelial cell PECAM-1 promo ...... ed flow in ApoE-deficient mice
@ast
Endothelial cell PECAM-1 promo ...... ed flow in ApoE-deficient mice
@en
prefLabel
Endothelial cell PECAM-1 promo ...... ed flow in ApoE-deficient mice
@ast
Endothelial cell PECAM-1 promo ...... ed flow in ApoE-deficient mice
@en
P2093
P2860
P1476
Endothelial cell PECAM-1 promo ...... ed flow in ApoE-deficient mice
@en
P2093
Andrew W Pryor
Anthony C Bruce
Bradley D Gelfand
Brett R Blackman
Brian L Harry
John M Sanders
Martin A Schwartz
Melissa Lansey
Ryan E Feaver
P2860
P304
P356
10.1161/ATVBAHA.108.164707
P407
P577
2008-08-07T00:00:00Z