Characterization of the siderophore of Francisella tularensis and role of fslA in siderophore production
about
Subversion of host recognition and defense systems by Francisella sppSystems approach to investigating host-pathogen interactions in infections with the biothreat agent Francisella. Constraints-based model of Francisella tularensisFeoB-mediated uptake of iron by Francisella tularensisParalogous outer membrane proteins mediate uptake of different forms of iron and synergistically govern virulence in Francisella tularensis tularensis.Two parallel pathways for ferric and ferrous iron acquisition support growth and virulence of the intracellular pathogen Francisella tularensis Schu S4Iron and Virulence in Francisella tularensis.The FupA/B protein uniquely facilitates transport of ferrous iron and siderophore-associated ferric iron across the outer membrane of Francisella tularensis live vaccine strain.The reduced genome of the Francisella tularensis live vaccine strain (LVS) encodes two iron acquisition systems essential for optimal growth and virulenceRequirement of the CXXC motif of novel Francisella infectivity potentiator protein B FipB, and FipA in virulence of F. tularensis subsp. tularensis.The fslE homolog, FTL_0439 (fupA/B), mediates siderophore-dependent iron uptake in Francisella tularensis LVS.fslE is necessary for siderophore-mediated iron acquisition in Francisella tularensis Schu S4Adaptation of Francisella tularensis to the mammalian environment is governed by cues which can be mimicked in vitro.A comprehensive transposon mutant library of Francisella novicida, a bioweapon surrogateGlobal transcriptional response to mammalian temperature provides new insight into Francisella tularensis pathogenesis.Modulation of iron homeostasis in macrophages by bacterial intracellular pathogens.Gallium disrupts iron uptake by intracellular and extracellular Francisella strains and exhibits therapeutic efficacy in a murine pulmonary infection model.Indoleamine 2,3-dioxygenase 1 is a lung-specific innate immune defense mechanism that inhibits growth of Francisella tularensis tryptophan auxotrophsMacrophage replication screen identifies a novel Francisella hydroperoxide resistance protein involved in virulence.The role of MglA for adaptation to oxidative stress of Francisella tularensis LVS.Evaluation of reference genes for reverse transcription quantitative PCR analyses of fish-pathogenic Francisella strains exposed to different growth conditions.Iron content differs between Francisella tularensis subspecies tularensis and subspecies holarctica strains and correlates to their susceptibility to H(2)O(2)-induced killingUse of a capture-based pathogen transcript enrichment strategy for RNA-Seq analysis of the Francisella tularensis LVS transcriptome during infection of murine macrophages.Regulation of francisella tularensis virulence.Francisella tularensis metabolism and its relation to virulence.Role of pathogenicity determinant protein C (PdpC) in determining the virulence of the Francisella tularensis subspecies tularensis SCHU.Mechanisms of heme utilization by Francisella tularensisIn vivo negative selection screen identifies genes required for Francisella virulenceThe major facilitator superfamily-type protein LbtC promotes the utilization of the legiobactin siderophore by Legionella pneumophilaThe Legionella pneumophila Siderophore Legiobactin Is a Polycarboxylate That Is Identical in Structure to Rhizoferrin.Comparative Transcriptional Analyses of Francisella tularensis and Francisella novicida.Identification of Francisella tularensis Himar1-based transposon mutants defective for replication in macrophagesLimited role for iron regulation in Coxiella burnetii pathogenesis.Identification of migR, a regulatory element of the Francisella tularensis live vaccine strain iglABCD virulence operon required for normal replication and trafficking in macrophages.Purification of Legiobactin and importance of this siderophore in lung infection by Legionella pneumophilaEnvironmental adaptation of Francisella tularensis.Intracellular biology and virulence determinants of Francisella tularensis revealed by transcriptional profiling inside macrophages.The 58-kilodalton major virulence factor of Francisella tularensis is required for efficient utilization of iron.Proteins involved in Francisella tularensis survival and replication inside macrophages.Characterization of microbial siderophores by mass spectrometry.Identification of differentially regulated francisella tularensis genes by use of a newly developed Tn5-based transposon delivery system.
P2860
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P2860
Characterization of the siderophore of Francisella tularensis and role of fslA in siderophore production
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Characterization of the sidero ...... fslA in siderophore production
@ast
Characterization of the sidero ...... fslA in siderophore production
@en
type
label
Characterization of the sidero ...... fslA in siderophore production
@ast
Characterization of the sidero ...... fslA in siderophore production
@en
prefLabel
Characterization of the sidero ...... fslA in siderophore production
@ast
Characterization of the sidero ...... fslA in siderophore production
@en
P2093
P2860
P356
P1476
Characterization of the sidero ...... fslA in siderophore production
@en
P2093
Erin Field Jeffery
Girija Ramakrishnan
John D Shannon
Jonathan Tabb Sullivan
P2860
P304
P356
10.1128/JB.00027-06
P407
P577
2006-06-01T00:00:00Z