Position of synaptotagmin I at the membrane interface: cooperative interactions of tandem C2 domains.
about
Regulation of intracellular membrane trafficking and cell dynamics by syntaxin-6Lateral diffusion of proteins on supported lipid bilayers: additive friction of synaptotagmin 7 C2A-C2B tandem domains.Molecular mechanism of the synaptotagmin–SNARE interaction in Ca2+-triggered vesicle fusionPhosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitmentCis- and trans-membrane interactions of synaptotagmin-1Membrane thickness varies around the circumference of the transmembrane protein BtuB.PtdInsP2 and PtdSer cooperate to trap synaptotagmin-1 to the plasma membrane in the presence of calcium.Synaptotagmin-1 binds to PIP(2)-containing membrane but not to SNAREs at physiological ionic strengthReconstituting SNARE-mediated membrane fusion at the single liposome level.The juxtamembrane linker of full-length synaptotagmin 1 controls oligomerization and calcium-dependent membrane binding.Synaptotagmin 1 modulates lipid acyl chain order in lipid bilayers by demixing phosphatidylserinePartitioning of synaptotagmin I C2 domains between liquid-ordered and liquid-disordered inner leaflet lipid phasesPhosphatidylinositol 4,5-bisphosphate alters synaptotagmin 1 membrane docking and drives opposing bilayers closer together.Synaptotagmin 1 and SNAREs form a complex that is structurally heterogeneous.Solution and membrane-bound conformations of the tandem C2A and C2B domains of synaptotagmin 1: Evidence for bilayer bridgingThe calcium-dependent and calcium-independent membrane binding of synaptotagmin 1: two modes of C2B binding.Conformation and membrane position of the region linking the two C2 domains in synaptotagmin 1 by site-directed spin labeling.Interaction of synaptotagmin with lipid bilayers, analyzed by single-molecule force spectroscopy.Membrane docking geometry of GRP1 PH domain bound to a target lipid bilayer: an EPR site-directed spin-labeling and relaxation study.Single molecule diffusion of membrane-bound proteins: window into lipid contacts and bilayer dynamics.Negative coupling as a mechanism for signal propagation between C2 domains of synaptotagmin I.Rubella virus: first calcium-requiring viral fusion protein.Membrane penetration by synaptotagmin is required for coupling calcium binding to vesicle fusion in vivo.Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation.Post-translational modifications and lipid binding profile of insect cell-expressed full-length mammalian synaptotagmin 1Dysferlin and muscle membrane repair.Protein-driven membrane stresses in fusion and fission.Calcium binding by synaptotagmin's C2A domain is an essential element of the electrostatic switch that triggers synchronous synaptic transmission.Different states of synaptotagmin regulate evoked versus spontaneous release.Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+.The Janus-faced nature of the C(2)B domain is fundamental for synaptotagmin-1 function.Genetic analysis of synaptotagmin C2 domain specificity in regulating spontaneous and evoked neurotransmitter release.Interactions of the GM2 activator protein with phosphatidylcholine bilayers: a site-directed spin-labeling power saturation study.Modeling membrane shaping by proteins: focus on EHD2 and N-BAR domains.Hydrophobic contributions to the membrane docking of synaptotagmin 7 C2A domain: mechanistic contrast between isoforms 1 and 7Non-Native Metal Ion Reveals the Role of Electrostatics in Synaptotagmin 1-Membrane Interactions.The Mechanisms and Functions of Synaptic Facilitation.Effect of PIP2 binding on the membrane docking geometry of PKC alpha C2 domain: an EPR site-directed spin-labeling and relaxation studySynaptotagmin-1 utilizes membrane bending and SNARE binding to drive fusion pore expansion.Differential Membrane Binding Mechanics of Synaptotagmin Isoforms Observed in Atomic Detail.
P2860
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P2860
Position of synaptotagmin I at the membrane interface: cooperative interactions of tandem C2 domains.
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Position of synaptotagmin I at ...... ractions of tandem C2 domains.
@ast
Position of synaptotagmin I at ...... ractions of tandem C2 domains.
@en
type
label
Position of synaptotagmin I at ...... ractions of tandem C2 domains.
@ast
Position of synaptotagmin I at ...... ractions of tandem C2 domains.
@en
prefLabel
Position of synaptotagmin I at ...... ractions of tandem C2 domains.
@ast
Position of synaptotagmin I at ...... ractions of tandem C2 domains.
@en
P2093
P356
P1433
P1476
Position of synaptotagmin I at ...... ractions of tandem C2 domains.
@en
P2093
Anne Hinderliter
David S Cafiso
Dawn Z Herrick
Katie A Rasch
Stephenie Sterbling
P304
P356
10.1021/BI060874J
P407
P577
2006-08-01T00:00:00Z